Posttraumatic stress disorders in the Nanai after pollution of the Amur River: ethnocultural analysis

Korshunova, N.V.; Katsuyama, Hironobu; Demura, Masashi; Tanii, Hideji; Katsuyama, Midori; Rahayu, Sri; Bogdanov, Nikolay Anatoljevich; Solokhina, L. V.; Saijoh, Kiyofumi

doi:10.1007/s12199-013-0346-6

Cited by 2 publications

(9 citation statements)

References 27 publications

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“…The participants and field-type survey have been described previously [ 3 ]. That is, 187 indigenous adult Nanai volunteers over the age of 18 years were randomly selected from the general civilian population in eight villages in the Nanai Regional District of Khabarovsk Territory located in the Far East of the Russian Federation.…”

Section: Methodsmentioning

confidence: 99%

“…PTSD severity, as determined via the participants’ Total-I and Total-C, was analyzed in association with the participants’ demographic and ethnocultural background, clinical examination results, and ethnopsychological attitude toward the Amur River; these data have been previously published [ 3 ]. Due to their discrepancy identified in the derived results, we proceeded to analyze the association between the participants’ personality/ego profiles and not only Total-I and Total-C but also specific items on the IES-R and CAPS.…”

Section: Methodsmentioning

confidence: 99%

“…PTSD examination: the precise method utilized for IES-R and CAPS administration has been described in a previous report [ 3 ]. Briefly, they are questionnaires consisted of four to eight questions scoring severity of Intrusion/Avoidance/Hyperarousal and their total.…”

Section: Methodsmentioning

confidence: 99%

“…Previously [ 3 ], PTSD severity has been assessed in this population using the Impact of Event Scale-Revised (IES-R) [ 4 – 6 ] and the Clinician-Administered PTSD Scale (CAPS) [ 7 , 8 ]. Both the IES-R and the CAPS consist of questions regarding Intrusion (compulsion to repeat), Avoidance of traumatic events, and Hyperarousal to physiological symptoms of irritability.…”

Section: Introductionmentioning

confidence: 99%

“…Severity was determined by assessing their total scores, IES-R total (Total-I) and CAPS total (Total-C). The results were not always identical and depended upon the participants’ demographic and ethnocultural background, clinical examination results, and ethnopsychological attitudes toward the Amur River [ 3 ]. The comparison of the results derived using the Total-I and the Total-C alone seemed to be insufficient to understand the severity of PTSD in this population.…”

Section: Introductionmentioning

confidence: 99%

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Association between posttraumatic stress disorder (PTSD) severity and ego structure of the Nanai people

Ota¹,

Korshunova²,

Demura³

et al. 2017

Environ Health Prev Med

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BackgroundA man-made chemical disaster occurred in the Amur River, leading to posttraumatic stress disorder (PTSD) in the Nanai people indigenous to the river’s surrounding area. PTSD severity measured by the total scores of Impact of Event Scale-Revised (IES-R) (Total-I) and Clinician-Administered PTSD Scale (CAPS) (Total-C) were not always identical in terms of demographic and ethnocultural characters. It is possible that the results derived using the Total-I and Total-C may differ for persons with different backgrounds and/or individual characteristics. In this study, the associations between PTSD severity and personal characteristics were evaluated.MethodsThe study was a field-type survey including 187 randomly selected participants (75 males and 112 females). In addition to Total-I/Total-C, scores for each IES-R/CAPS item, Intrusion, Avoidance, and Hyperarousal, and Ego Structure Test by Ammon (ISTA) score were examined to evaluate their personal characteristics.ResultsNo specific trends in ISTA score were obvious among four groups defined according to Total-I/Total-C. The results of principal component analysis showed that all IES-R/CAPS items contributed positively to the 1st axis but to the 2nd axis in a different manner. ISTA items did not always show correlations to each other, but principal component analysis suggested that Construct contributed positively and Destruct and Deficient (with the exception of Destruct sexuality) contributed negatively. High IES-R scores were associated with Construct Aggression and Deficient Inner demarcation, but high CAPS score was less likely to exhibit Construct Narcissism.ConclusionTo avoid the misdiagnosis of PTSD, usage of both IES-R/CAPS may be required. Simultaneous application of personality/ego tests may be helpful, but appropriate numbers of their questions would be important.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Association between posttraumatic stress disorder (PTSD) severity and ego structure of the Nanai people

Ota¹,

Korshunova²,

Demura³

et al. 2017

Environ Health Prev Med

Self Cite

View full text Add to dashboard Cite

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Comparison of CYP2C9, CYP2C19, CYP2D6, ABCB1, and SLCO1B1 gene-polymorphism frequency in Russian and Nanai populations

Sychev

Шуев

Suleymanov³

et al. 2017

PGPM

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BackgroundThe efficiency and safety of drug therapy depends on the peculiarities of functioning of the P450 cytochrome group and transporting proteins. There are significant differences for single-nucleotide polymorphism (SNP) frequency.Materials and methodsWe studied the peculiarities of P450 cytochrome polymorphisms, SLCO1B1 transporting protein, and P-glycoprotein carriage in healthy volunteers in the Nanai ethnic group living in Russia, and compared them to the carriage of SNPs in the Russian population according to literature data.ResultsAfter performing the real-time polymerase chain reactions on the samples from 70 healthy volunteers from the Nanai group, for the CYP2C9*2C430T polymorphism we determined 70 CC-genotype carriers. As for the CYP2C9*3A1075C polymorphism, we found 62 AA-genotype carriers and eight AC-genotype carriers. For the CYP2C19*2G681A polymorphism, we determined 39 GG-genotype carriers and 28 GA-genotype carriers, for the CYP2C19*3G636A polymorphism 58 GG-genotype carriers and 12 GA-genotype carriers, and for the CYP2C19*17C806T polymorphism 67 CC-genotype carriers and three CT-genotype carriers. For the CYP2D6*4G1846A polymorphism, the GG genotype had 68 carriers, and the GA genotype two carriers. For the ABCB1*6C3435T polymorphism, there were 19 CC-genotype carriers and 39 CT-genotype carriers. For the SLCO1B1*5T521C polymorphism, the TT genotype had 41 carriers and the CT genotype 25 carriers. The distribution of genotypes fitted the Hardy–Weinberg equilibrium for all the polymorphisms, except those of CYP2C9*2. There were also significant differences in allele frequencies for some polymorphisms between the Nanais and the Russians.ConclusionIn the Nanai population, there are polymorphisms connected with the decrease in safety and efficiency of drug therapy. Studying the ethnic differences might influence the determination of priority in the introduction of pharmacogenetic tests in clinical practice in different regions of Russia.

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Posttraumatic stress disorders in the Nanai after pollution of the Amur River: ethnocultural analysis

Abstract: Those with a pragmatic attitude were less likely to have PTSD. However, those who were required to make decisions within close relationships and were intimate with the Nanai tradition and the Amur River had increased likelihood of PTSD.

Cited by 2 publications

References 27 publications

Association between posttraumatic stress disorder (PTSD) severity and ego structure of the Nanai people

Association between posttraumatic stress disorder (PTSD) severity and ego structure of the Nanai people

Comparison of <em>CYP2C9</em>, <em>CYP2C19</em>, <em>CYP2D6</em>, <em>ABCB1</em>, and <em>SLCO1B1</em> gene-polymorphism frequency in Russian and Nanai populations

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