Potent Typing Sera Produced by Treatment of Donors with Isolated Blood Group Specific Substances.

Erythrocytes in human transplantation: effects of pretreatment with ABO group-specific antigens

“…Pretreatment of group 0 recipients with soluble A substance, however, resulted in significant elevations in anti-A antibody titers (44). As noted in Fig.…”

Preparation of Anti-A(1) Sera Using Hog Stomach Extracts

“…It has been known for many years that hog stomach is a good source of A substance and some donors have received injections of groups specific substance derived from this organ in order to produce potent typing sera [11]. There is, however, no report of hog stomach extracts being used to neutralize the anti-A of group B sera in the preparation of anti-Ax sera.…”

Studies With Inagglutinable Erythrocyte Counts. Iii. Kinetics of Erythrocyte Destruction in Human Beings 1

“…Anti-A and anti-B agglutinating sera were collected from human donors of appropriate blood group who had been immunized by repeated injections of the A and B substances of Witebsky, Klendshoj and McNeil, (30). Each lot of serum was divided into small aliquots sufficient for one day's testing.…”