2015
DOI: 10.1097/iop.0000000000000240
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Potential Correlation Between Menopausal Status and the Clinical Course of Orbital Cavernous Hemangiomas

Abstract: In this study evaluating orbital cavernous hemangiomas over a span of 30 years, the authors found that in postmenopausal women with assumed decreasing levels of circulating estrogen/progesterone, the vast majority of lesions either remained stable or decreased in size, suggesting the effect of hormone levels on such vascular lesions and supporting the role for observation in asymptomatic individuals in this patient population.

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Cited by 28 publications
(18 citation statements)
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“…The condition is more prevalent in women, and recent reports suggest that female sex hormones may play a role in clinical presentation. 5 Ultrasound, CT, or MRI typically establishes a diagnosis of IMH. However, ultrasound is inferior to CT and MRI regarding the location of lesion and relationship with surrounding structures.…”
Section: Discussionmentioning
confidence: 99%
“…The condition is more prevalent in women, and recent reports suggest that female sex hormones may play a role in clinical presentation. 5 Ultrasound, CT, or MRI typically establishes a diagnosis of IMH. However, ultrasound is inferior to CT and MRI regarding the location of lesion and relationship with surrounding structures.…”
Section: Discussionmentioning
confidence: 99%
“…Orbital cavernous hemangiomas present between 20 and 60 years of age and are more common in women. Jayaram et al 17 has postulated a role of menopause, showing that in patients who were postmenopausal and were presumed to have decreasing levels of estrogen and progesterone, lesions decreased in size or remained stable. Regarding tumor laterality, a retrospective study of 104 patients with orbital cavernous hemangiomas shows slight left-sided predominance (53.8%) 18 with rare bilateral involvement.…”
Section: Cavernous Hemangioma (Cavernous Venous Malformation)mentioning
confidence: 99%
“…CHMs are more common among women (60-70%), potentially because of hormone level (7). The onset age ranges from 17 to 86 years (mean, 45 years).…”
Section: Clinical Characteristicsmentioning
confidence: 99%