Potential for industrial products from the halophilic Archaea

Litchfield, Carol D.

doi:10.1007/s10295-011-1021-9

Cited by 87 publications

(53 citation statements)

References 86 publications

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“…Members of the Halobacteriaceae have a number of useful applications, and potential new applications in biotechnological processes are being investigated (Galinski and Tindall 1992;Litchfield 2011;Margesin and Schinner 2001;Oren 2010; The Family Halobacteriaceae Rodriguez-Valera 1992; Ventosa and Nieto 1995). The following list presents some of the current and potential future applications of the group:…”

Section: Applicationmentioning

confidence: 99%

The Family Halobacteriaceae

Oren

2014

The Prokaryotes

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Section: Applicationmentioning

confidence: 99%

The Family Halobacteriaceae

Oren

2014

The Prokaryotes

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“…Cellulases take an important share in the worldwide enzyme market owed to their various uses including cotton processing, paper recycling, detergent formulation, juice extraction, and animal feed additives for uses in agricultural biotechnology and production of transportation fuel (bioenergy) besides bio based products [35][36][37]. Amongst thermophilic bacteria, Bacillus species producing some extracellular polysaccharide-hydrolyzing enzymes, which consist of cellulose.…”

Section: Enzymesmentioning

confidence: 99%

An Overview of Saltpan Halophilic Bacterium

Manikandan¹,

Pk²

2017

J Antimicrob Agents

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Hypersaline environments provide an excellent medium for natural microbial communities which serve as a potential source of pharmaceutical substances. Salt is widely present in the earth. Almost 73% of earth was covered with marine water which contains 2.5% of common salt. Protease enzyme activity widespread in microorganisms, plant and animals. Proteolytic enzymes used in the industrial application and bioremediation process. In recent years' new mutant's microbe resistant to commonly used antibiotics. Protease inhibitors used as potential antibiotics for controlling microbial infections. A Hypersaline environment such as salt pans and salt lakes has high salt concentration and pH. The saltpan provides a diversity of different environmental conditions of alkalinity, salinity, temperature, pH and nutrition. Halophilic organisms growing between 0.5 and 3.0 M salt concentration. Extreme environments are the best source of bioactive compound producing halophiles microbes.

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“…Many halophilic enzymes can work under low water activity, in the presence of organic solvents [179] and, in some cases, at high temperatures [180]. By doing the enzymatic reactions in organic solvent media, there would not be any possibility of microbial contamination or unwanted water-related reactions.…”

Section: Halophilic Enzymes -Potential Industrial Applicationsmentioning

confidence: 99%

Systematics of haloarchaea and biotechnological potential of their hydrolytic enzymes

et al. 2017

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Halophilic archaea, also referred to as haloarchaea, dominate hypersaline environments. To survive under such extreme conditions, haloarchaea and their enzymes have evolved to function optimally in environments with high salt concentrations and, sometimes, with extreme pH and temperatures. These features make haloarchaea attractive sources of a wide variety of biotechnological products, such as hydrolytic enzymes, with numerous potential applications in biotechnology. The unique trait of haloarchaeal enzymes, haloenzymes, to sustain activity under hypersaline conditions has extended the range of already-available biocatalysts and industrial processes in which high salt concentrations inhibit the activity of regular enzymes. In addition to their halostable properties, haloenzymes can also withstand other conditions such as extreme pH and temperature. In spite of these benefits, the industrial potential of these natural catalysts remains largely unexplored, with only a few characterized extracellular hydrolases. Because of the applied impact of haloarchaea and their specific ability to live in the presence of high salt concentrations, studies on their systematics have intensified in recent years, identifying many new genera and species. This review summarizes the current status of the haloarchaeal genera and species, and discusses the properties of haloenzymes and their potential industrial applications. SYSTEMATICS OF HALOPHILIC ARCHAEAHalophilic micro-organisms are found in the three domains of life, and are extremophiles living in hypersaline environments in the presence of salt (generally NaCl) as a specific requisite for their growth [1]. Hypersaline environments contain higher salt concentrations than seawater (3.5 % total dissolved salts) [2]. According to the optimum NaCl concentration for growth, micro-organisms fall into one of the following categories: extreme halophiles with optimum growth at 15-30 % (2.5-5.2 M) NaCl; moderate halophiles with optimum growth at 3-15 % (0.5-2.5 M) NaCl; slight halophiles with optimum growth at 1-3 % (0.2-0.5 M) NaCl; non-halophiles with optimum growth at less than 1 % (0.2 M) NaCl; and halotolerant micro-organisms which are non-halophiles showing the ability to tolerate high NaCl concentrations [3]. Halophiles can live in hypersaline environments because they are able to sustain osmotic balance. They use two main strategies to withstand the adverse consequences of water loss when exposed to high salt concentrations. The first strategy used by extremely halophilic archaea (haloarchaea) and halophilic anaerobic bacteria such as members of Halanaerobiales is known as the 'salt-in-cytoplasm' strategy, during which salts such as NaCl or KCl accumulate in the cytoplasm at concentrations similar to the extracellular ones [4,5]. Another mechanism to cope with high salt concentrations is the accumulation of organic molecules such as amino acids, sugars and polyols, known as compatible solutes or osmolytes. Compatible solutes are small and highly soluble molecules that can...

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Potential for industrial products from the halophilic Archaea

Cited by 87 publications

References 86 publications

The Family Halobacteriaceae

The Family Halobacteriaceae

An Overview of Saltpan Halophilic Bacterium

Systematics of haloarchaea and biotechnological potential of their hydrolytic enzymes

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