2024
DOI: 10.1101/2024.05.29.24308112
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Potential impact of switching from a two- to one-dose gender-neutral routine HPV vaccination program in Canada: A mathematical modeling analysis

Mélanie Drolet,
Jean-François Laprise,
Éléonore Chamberland
et al.

Abstract: BackgroundWorldwide, countries are examining whether to implement one-dose HPV vaccination. To inform policy recommendations in Canada, we used mathematical modeling to project the population-level impact and efficiency of switching from two-to one-dose gender-neutral routine HPV vaccination.MethodsWe used HPV-ADVISE, an individual-based transmission-dynamic model of HPV infections/diseases, to model 2 provinces (Quebec, Ontario), which represent higher (≈85%) and lower (≈65%) HPV vaccination coverage in Canad… Show more

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