Potential Medicinal Plants Used by the Tribal of Deogarh District, Orissa, India

Sahu, Sudam Charan; Dhal, Nabin Kumar; Mohanty, R. C.

doi:10.1080/09735070.2010.11886362

Cited by 18 publications

(4 citation statements)

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“…Today, natural products still have a huge importance as a source of new drugs and leads. Approximately 60% of anticancer compounds and 75% of drugs for infectious disease come from natural products or their derivatives [1–4]. In order to develop new drugs, different plants are being selected randomly or based on ethnobotanic and ethnopharmacologic knowledge.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and Antiproliferative Activities of Leaf Extracts fromPlukenetia volubilisLinneo (Euphorbiaceae)

Nascimento

Melo-Silveira

Dantas-Santos

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Plukenetia volubilis Linneo, or Sacha inca, is an oleaginous plant from the Euphorbiaceae family. The aim of this work was to perform a chemical and biological analysis of different leaf extracts from P. volubilis such as aqueous extract (AEL), methanol (MEL), ethanol (EEL), chloroform (CEL), and hexane (HEL). Thin layer chromatography analysis revealed the presence of phenolic compounds, steroids, and/or terpenoídes. Furthermore, the antioxidant activities were analyzed by in vitro assays and their effects on cell lineages by in vivo assays. The Total Antioxidant Capacity (TCA) was expressed as equivalent ascorbic acid (EEA/g) and it was observed that the extracts showed values ranging from 59.31 to 97.76 EAA/g. Furthermore, the DPPH assay values ranged from 62.8% to 88.3%. The cell viability assay showed that the extracts were able to reduce viability from cancer cells such as HeLa and A549 cells. The extracts MEL and HEL (250 µg/mL) were able to reduce the proliferation of HeLa cells up to 54.3% and 48.5%, respectively. The flow cytometer results showed that these extracts induce cell death via the apoptosis pathway. On the other hand, the extracts HEL and AEL were able to induce cell proliferation of normal fibroblast 3T3 cells.

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Section: Introductionmentioning

confidence: 99%

Antioxidant and Antiproliferative Activities of Leaf Extracts fromPlukenetia volubilisLinneo (Euphorbiaceae)

Nascimento

Melo-Silveira

Dantas-Santos

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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“…People of this region have rich knowledge of traditional medicine, especially in folk medicine. The impact of biotic factors such as urbanization, and industrialization which have caused the loss of forests have resulted in the loss of biodiversity as well as indigenous knowledge in different regions of Odisha [2][3][4][5][6][7][8][9][10] . Phytochemical analysis of ethno-medicinal plants as well as their antimicrobial activities provides much relevant information for the authentication of the medicinal properties of these plants [11][12] .…”

Section: Introductionmentioning

confidence: 99%

Indigenous knowledge and phytochemical analysis of potential medicinal plants of Kuldiha wildlife sanctuary in Odisha, India

Behera,

Nayak

2023

J. Med. Plants Stud.

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Kuldiha wildlife sanctuary in the Balasore district of the state of Odisha in India is endowed with rich biodiversity including medicinal plants. People of various ethnic groups in this region have rich indigenous knowledge about the medicinal plants, which are used for the treatment of various ailments. During the present investigation, ethno-medicinal studies have been conducted in different locations of Kuldiha wildlife Sanctuary and its adjoining regions. Phytochemical analysis of some potential medicinal plants reveals the presence of some phytochemicals such as alkaloids, flavonoids, terpenoids, glycosides, phenol, tannin, and saponin which are responsible for their medicinal properties and provide evidence for the validation of the ethno medicinal data for further use. Further studies on these plants' quantitative phytochemical analysis and antimicrobial activities will provide much useful information for their applications in the herbal drug industry.

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“…Approximately 60% of anticancer compounds and 75% drugs for infectious diseases come from natural products or their derivatives. [1][2][3][4][5] Plants have contributed hugely to western medicine, through providing ingredients for drugs or having played central role in drug discovery.…”

Section: Introductionmentioning

confidence: 99%

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2016

IJPSR

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Anti cancer activity of four selected mangrove plants Bruguiera gymnorrhiza, Aegiceras corniculatum, Aegialitis rotundifolia and Lumnitzera racemosa against HepG2 cell line was studied. During the present investigation, crude methanol extracts of selected mangrove plants were prepared using soxhlet apparatus. In vitro anti cancer activity of mangrove plant extracts at various concentrations (10 to 200ug/ml) was studied against the chosen cell line using MTT assay (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide). All the four extracts showed anti cancer activity. Off which methanolic extract of Bruguiera gymnorrhiza has shown lower IC 50 value than Aegialitis rotundifolia, Lumnitzera racemosa, Aegiceras corniculatum respectively, indicating its greater anti cancer activity. The present study indicates that the methanolic mangrove plant extracts were effective against tumor cells and possess anticancer activity.

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Potential Medicinal Plants Used by the Tribal of Deogarh District, Orissa, India

Cited by 18 publications

References 1 publication

Antioxidant and Antiproliferative Activities of Leaf Extracts fromPlukenetia volubilisLinneo (Euphorbiaceae)

Antioxidant and Antiproliferative Activities of Leaf Extracts fromPlukenetia volubilisLinneo (Euphorbiaceae)

Indigenous knowledge and phytochemical analysis of potential medicinal plants of Kuldiha wildlife sanctuary in Odisha, India

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