Potential use of turmeric in COVID‐19

Abstract

Turmeric ( Curcuma longa L.) is an integral part of Asian culture which has been used in traditional medicine systems like Ayurveda, Unani and Siddha owing to its wide array of medicinal properties since centuries. Curcumin, the predominant curcumoid in turmeric, influences multiple signaling pathways and been found to possess anti‐inflammatory, anti‐oxidant, antimicrobial, hypoglycemic, wound healing, chemopreventive, chemosensitising and radiosensitising properties. 1 To enhance the bioavailability of curcumin, newer technologies such as adjuvant, nanoparticles, liposomes, micelles and phospholipid complexes are evaluated in the process of drug development. It is documented to be most efficacious in high doses at around 6‐7 gm per day which is well tolerated orally. 1 It has been widely used as a common household remedy for cough, sore throat and respiratory ailments in Asia.

Can Echinacea be a potential candidate to target immunity, inflammation, and infection - The trinity of coronavirus disease 2019

“…Recently, studies have suggested the repurposing of curcumin [ 180 ], glycyrrhizin [ 181 ], thymoquinone [ 182 ], and polyphenolic flavonoids [ 183 ] for COVID-19 owing to their potential to exert synergistic or additive effects including antiviral, anti-inflammatory, immunomodulatory, and antioxidant activities, with no systemic toxicity. Although, the interaction and risks appear to have negligible therapeutic concern [ 184 ].…”

Molecular Mechanisms of Curcumin in COVID-19 Treatment and Prevention: A Global Health Perspective

“…It is important to note the significant intersection of COVID-19 systemic manifestations and the benefits of curcumin administration noted herein, and by several others that have examined curcumin as a preventative or treatment option. [89][90][91] In every system where COVID-19 seems to manifest, including the CNS, curcumin has broad spectrum coverage of the associated inflammatory symptoms.…”

Home remedies in different pediatric dermatoses: An observational study

“…11,12 Turmeric, a commonly used Indian condiment, has been found to contain Curcumin which has anti-inflammatory, anti-oxidant, antimicrobial, anti-viral, wound healing, chemopreventive, chemosensitising, and radiosensitising properties and is commonly used for skin lightening and wound healing in traditional Indian medicine. 13,14 Fuller's earth (Mul- Even though the traditional home remedies are useful, but many products can have various adverse effects also. Mustard oil is a commonly used home remedy for a wide variety of skin disorders but it has been known to cause contact dermatitis and irritant reactions by disrupting the skin barrier function.…”

“…Apart from inhibition of microbes responsible for wound infections, honey has been shown to inhibit the growth of dermatophyte, Candida albicans and Propionibacterium acnes 11,12 . Turmeric, a commonly used Indian condiment, has been found to contain Curcumin which has anti‐inflammatory, anti‐oxidant, antimicrobial, anti‐viral, wound healing, chemopreventive, chemosensitising, and radiosensitising properties and is commonly used for skin lightening and wound healing in traditional Indian medicine 13,14 . Fuller's earth ( Multani mitti ) is another common home remedy used in Indian subcontinent, which is essentially a clay consisting of aluminium silicate.…”