Potentials in synthesizing nanostructured silver particles

Ramanathan, Santheraleka; Gopinath, Subash C.B.

doi:10.1007/s00542-017-3382-0

Cited by 45 publications

(26 citation statements)

References 51 publications

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“…Despite their size, nanomaterial can change color in response to variations in their forms, such as bulk, sheets, or in cylinders. Nanomaterial has been widely applied for various biotechnological and biomedical purposes . Recently, carbon nanotubes have received a great deal of attention.…”

Section: Introductionmentioning

confidence: 99%

“…The plant extracts have different medicinal values, generated by the traditional system and also extracted from the indigenous species. The efficient usage of the components from plant extract depends on the stability; immobilization is one of the strategies to make these stable components . Among different herbal plants, “ Andrographis paniculata ( Hempedu bumi )” is one of the potential plants for the remedial source, which can be found in southern and south‐eastern regions of the Asia.…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial activity of functionalized single‐walled carbon nanotube with herbal extract of Hempedu bumi

Foo

Anbu

Gopinath

et al. 2018

Surface & Interface Analysis

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The primary purpose of this study was to determine the antimicrobial activity of functionalized single-walled carbon nanotube (SWNT) using an extract of the herb, Hempedu bumi. H bumi extract and H bumi extract complexed SWNT were evaluated for biological activities against Bacillus sp., (pathogen) Escherichia coli (opportunistic pathogen), and Aspergillus niger (pathogen).The formation of inhibition zones of these 3 microbes was measured to be evident for the functionalized SWNT with H bumi. Further, morphological and structural analyses were conducted to investigate the functionalized SWNT with H bumi using scanning electron microscopy, atomic force microscopy, X-ray photoelectron spectroscopy, X-ray powder diffraction, and Fourier transform infrared spectroscopy, well supporting the intact and crystalline nature of the SWNT. Fourier transform infrared spectroscopy result shows the highest peak at 3371.48 cm −1 , representing an andrographolide group from the plant extract. An apparent clear zone has been noticed with SWNT conjugated H bumi extract, displaying a zone of inhibition larger than 1.0 cm against the tested microbes. The results indicate that SWNT has the potential for use as a carrier of components from plant extracts.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antimicrobial activity of functionalized single‐walled carbon nanotube with herbal extract of Hempedu bumi

Foo

Anbu

Gopinath

et al. 2018

Surface & Interface Analysis

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“…Currently, nanotechnology is a booming discipline implemented effectively in various sectors. The development of high-performance nanomaterials could be a central importance for medical diagnosis, target validation and drug-delivery [1][2][3][4][5][6]. Careful selection of proper nanomaterials is aiding to interacting biomolecules for various downstream applications.…”

Section: Introductionmentioning

confidence: 99%

Engineered nanostructures to carry the biological ligands

Gopinath

Ramanathan

Suk

et al. 2018

MATEC Web of Conferences

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Different nanostructures were engineered with the nanoscale dimension lesser than 100 nm. These nanostructures include silver, cellulose nanoparticles and single-walled carbon nanotube (SWCNT). Biological ligands were obtained from the medicinally important herbal plants, such as Solanum trilobatum and Hempedu bumi and conjugated with the nanostructures silver nanoparticle and SWCNT, respectively. On the other hand, bio-ligands from cow urine were encapsulated in the cellulose nanoparticle. To confirm morphology these nanostructures, they were observed under Field Emission Scanning Electron Microscope and the results displayed the uniformed nanostructures. Further, biological ligand carrying ability of these nanostructures was confirmed by the bacterial inhibition assay on the agar plate. This study provided the evidence on the capability of nanostructures to carry the biological ligands.

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“…Before the existence of microbes was discovered, humans believed that plants have healing properties, reflecting the current antimicrobial characterization principles [1,2]. Formerly, humans utilized plants to treat infectious diseases, and the so-called "traditional medicines" are still being used for the treatment of various illnesses [3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Potential of Andrographis paniculata Conjugated Gold Nanoparticle

Razalli¹,

Gopinath²,

Kasim³

et al. 2019

INNOCS Theranos Pharmco Sci

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Background: Herbal extracts have been traditionally used as antibacterial agents, and different strategies have been proposed to enhance their antimicrobial activities. This research aimed to assess the antimicrobial potential of Andrographis paniculata conjugated gold nanoparticle (GNP) compounds against Escherichia coli and Bacillus subtilis.Methods: Herbal extract was conjugated with GNP through electrostatic interaction, and characterization was carried out by Fourier-transmission infrared spectroscopy, screening electron microscopy, and transmission electron microscopy and supported by energy-dispersive X-ray spectroscopy. Antibacterial activity of the herbal extract and GNP conjugation was evaluated by disc diffusion assay.Results: Chemical and morphological characterizations of the GNP and herbal extract conjugate revealed intactness of the GNP. In disc diffusion assay, the inhibition zone formed by these compounds was measured for both microorganisms, and they were in the range of 0.6-0.9 cm for the herbal extract. When the herbal extract conjugated with GNP, the zone was between 0.8 and 1.1 cm.Conclusion: This study demonstrated the potentiality of GNP to carry the antibacterial compounds from the herbal extract.

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Potentials in synthesizing nanostructured silver particles

Cited by 45 publications

References 51 publications

Antimicrobial activity of functionalized single‐walled carbon nanotube with herbal extract of Hempedu bumi

Antimicrobial activity of functionalized single‐walled carbon nanotube with herbal extract of Hempedu bumi

Engineered nanostructures to carry the biological ligands

Antimicrobial Potential of Andrographis paniculata Conjugated Gold Nanoparticle

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