“…The results are reported referenced to a six-level Spencer logarithmic scale, and higher grades have been associated with larger right-to-left shunts. 111,112 The advantages of TCD over TEE and TTE include increased patient comfort (compared with TEE), semiquantitative assessment of shunt size, and the ability to identify extracardiac and intracardiac shunting. The identification of extracardiac shunts is also a limitation of TCD, because no anatomic information is provided regarding the location of the shunt or associated abnormalities.…”