2010
DOI: 10.3892/or_00000895
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PPARγ polymorphisms and cancer risk: A meta-analysis involving 32,138 subjects

Abstract: Abstract. The peroxisome proliferator-activated receptor Á (PPARÁ) has been suggested to act as a tumor suppressor gene. Two common variations of PPARÁ, P12A (Pro12Ala, rs1801282) and C161T (His447His, rs3856806), are thought to have an effect on susceptibility to various carcinomas but the results are inconsistent. In this meta-analysis, we assessed published studies of the association between two common PPARÁ polymorphisms and cancer risk from 26 studies with 27,677 subjects for PPARÁ P12A, from 4 studies wi… Show more

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Cited by 8 publications
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