Practical application of brief cognitive tests

Olazarán, Javier; Hoyos-Alonso, M Canto de; Ser, Teodoro del; Barral, Araceli Garrido; Conde-Sala, Josep Lluís; Bermejo‐Pareja, Félix; López-Pousa, Secundino; Pérez-Martínez, D A; Villarejo-Galende, Alberto; Cacho, Jesus L.; Navarro, Elisa; Oliveros‐Cid, Antonio; Peña-Casanova, Jordi; Carnero-Pardo, C.

doi:10.1016/j.nrleng.2015.07.005

Cited by 15 publications

(13 citation statements)

References 68 publications

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“…8 Because of this, the administration of verbal fluency tests has been proposed for screening of cognitive deficiency in patients with impairment in executive functions, such as Parkinson's, 9 multiple sclerosis, 10 or dementia. 11 Consistent with clinical observations, neuroimaging studies on healthy people have revealed the involvement of overlapping, but not the same, brain circuits in both tasks. SF was found to be associated with activation in ventral-anterior left inferior frontal gyrus, whereas PF was found to be represented in the posterior-dorsal left frontal gyrus 12,13 as well as in presupplementary motor area and left caudate.…”

Section: Introductionsupporting

confidence: 59%

Verbal Fluency Test in Children with Neurodevelopmental Disorders

Paz

Puga

Ekonen

et al. 2020

JNRP

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BackgroundThe verbal fluency task is a widely used psychometric test to account for cognitive functions, particularly, verbal and executive functions. Being an easy and fast test to administer, it is a good neuropsychological tool in low technology environments. Our objective was to analyze the performance in verbal fluency of Spanish-speaking children with neurodevelopmental disorders. Methods We performed a retrospective cross-sectional study to analyze the performance of children who had undergone a verbal fluency test in a neuropsychological assessment.Results We included 115 participants. There were 41 (35.65%) participants with low intellectual performance (LIP), 63 (54.78%) with attention deficit hyperactive disorder (ADHD), and 11(9.57%) participants with dyslexia. Participants with LIP showed lower phonological and semantic fluency scores than participants with ADHD, and a lower performance in semantic fluency than the dyslexia group. The probability of having LIP was 6.12 times greater when somebody had a scale score lower than 7 in the phonological task and it was 7.9 times greater when the scale score was lower than 7 in the semantic task. Conclusion There was a direct relationship between Full Scale Intelligence Quotient and verbal fluency test performance, the latter being a brief and effective neuropsychological test that can reveal deficit not only in executive functions and verbal abilities but also detect LIP. AbstractKeywords ► neuropsychological test ► verbal fluency test ► language disorders ► executive function

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Section: Introductionsupporting

confidence: 59%

Verbal Fluency Test in Children with Neurodevelopmental Disorders

Paz

Puga

Ekonen

et al. 2020

JNRP

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“…In order to intervene as early as possible at the initial stages of decline, it is necessary to have instruments for the detection of both MCI and major neurocognitive disorder. Brief cognitive screening tests (i.e., administered in less than 20 minutes— Olazaran et al, 2016 ) are often the initial step in the evaluation of patients with suspected cognitive impairment, and can be used by both specialists and Primary Care professionals, but are not intended to confirm diagnosis by themselves (which would require a combination of tools, included a further in-depth neuropsychological assessment). These brief tests may lead to erroneous clinical interpretations, as many rely on a high demand of reading and writing abilities ( Rosetti et al, 1990 ).…”

Section: Introductionmentioning

confidence: 99%

Cognitive Screening Instruments for Older Adults with Low Educational and Literacy Levels: A Systematic Review

Pellicer-Espinosa

Díaz-Orueta

2021

J Appl Gerontol

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This study presents a systematic review on existing cognitive screening tools for mild cognitive impairment and dementia in populations with low education and literacy levels. Cochrane Library, PubMed and LILACS databases were examined for studies including adults aged 50 years old or older with low educational level. 61 articles were included. Despite its frequent use, studies on Mini-Mental State Examination (MMSE) revealed that educational level biased the score obtained, regardless of other factors. Separately, the Informant Questionnaire on Cognitive Decline in the Elderly, the Fototest, or the Eurotest, appear to minimize the effect of education and literacy. MMSE is unreliable for individuals with low literacy. Tasks involving reading, writing, arithmetics, drawing, praxis, visuospatial, and visuoconstructive skills have a greater educational bias than naming, orientation, or memory. An adequate determination of educational level and validation of instruments in populations with heterogeneous levels of literacy requires further research.

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“…Besides, we have focused on the MMSE test as a proxy for cognitive impairment, as it is the most widely used given its rapid clinical application and the proper information it offers in patients with typical Alzheimer's disease [ 19 ].…”

Section: Discussionmentioning

confidence: 99%

The Genetic Research in Alzheimer Disease (GERALD) Initiative Finds rs9320913 as a Neural eQTL of lincRNA AL589740.1

Lopez-Gutierrez

García‐Alberca

Mendoza

et al. 2021

International Journal of Alzheimer's Disease

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Alzheimer’s disease is the most common cause of dementia worldwide, and longitudinal studies are crucial to find the factors affecting disease development. Here, we describe a novel initiative from southern Spain designed to contribute in the identification of the genetic component of the cognitive decline of Alzheimer’s disease patients. The germline variant rs9320913 is a C>A substitution mapping within a gene desert. Although it has been previously associated to a higher educational achievement and increased fluid intelligence, its role on Alzheimer’s disease risk and progression remains elusive. A total of 407 subjects were included in the study, comprising 153 Alzheimer disease patients and 254 healthy controls. We have explored the rs9320913 contribution to both Alzheimer disease risk and progression according to the Mini-Mental State Exams. We found that rs9320913 maps within a central nervous system lincRNA AL589740.1. eQTL results show that rs9320913 correlated with the brain-frontal cortex ( beta = − 0.15 , p value = 0.057) and brain-spinal cord (beta of -0.23, p value = 0.037). We did not find rs9320913 to be associated to AD risk, although AA patients seemed to exhibit a less pronounced Mini-Mental State Exam score decline.

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Practical application of brief cognitive tests

Cited by 15 publications

References 68 publications

Verbal Fluency Test in Children with Neurodevelopmental Disorders

Verbal Fluency Test in Children with Neurodevelopmental Disorders

Cognitive Screening Instruments for Older Adults with Low Educational and Literacy Levels: A Systematic Review

The Genetic Research in Alzheimer Disease (GERALD) Initiative Finds rs9320913 as a Neural eQTL of lincRNA AL589740.1

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