“…It has been identified as a predictor of severity in AP, but it increases late (during the first 24-48 hours), directly related with the degree of the necrosis [19]. Other authors consider that it is a sensitive predictor of the progression of severity from moderate to severe [14]; the results of its accuracy in predicting severity and mortality vary in different studies according to the time of measurement and the cutoff value used to measure it [7,8,9,14,19,26]. Plasma levels above 150mg/L within the first 72 hours of disease correlate with the presence of necrosis with a sensitivity and specificity that are both >80% [9].…”