Practical guidelines for the treatment of chronic nonspecific low back pain and comorbid chronic insomnia: clinical observation

Головачева, В. А.; Golovacheva, A. A.; Golubev, V L

doi:10.21518/2079-701x-2021-10-164-170

Cited by 12 publications

(3 citation statements)

References 24 publications

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“…26,49 Other investigators have suggested that increased cLBP symptoms in adults with insomnia may be related to altered pain modulation and central sensitization. 50 However, the molecular mechanism linking insomnia, central sensitization, and worse functional performance in cLBP remains under-explored.…”

Section: Discussionmentioning

confidence: 99%

The pace of biological aging helps explain the association between insomnia and chronic low back pain

Aroke,

Wiggins,

Hobson

et al. 2023

Mol Pain

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Chronic low back pain (cLBP) is associated with insomnia and advanced age. Emerging evidence suggests that the severity of both sleep disorders (like insomnia) and chronic pain are associated with a faster pace of biological aging. We aimed to determine whether the pace of biological age mediates the relationship between insomnia and the impact of cLBP in a sample of community-dwelling adults ages 19 to 85 years. Participants (49 with no pain, 32 with low-impact pain, and 37 with high-impact pain) completed sociodemographic, pain, insomnia, and short physical performance battery assessments. We calculated the pace of biological aging using DunedinPACE from blood leukocyte DNA. On average, individuals with high-impact cLBP had significantly faster biological aging than those with low-impact and no chronic pain (p < 0.001). Bivariate associations of DunedinPACE scores with insomnia severity and functional performance were significant at p < 0.01 (rs = 0.324 and -0.502, respectively). After adjusting for race and sex, the association of insomnia severity and the impact of cLBP was partially mediated by the pace of biological aging (β = 0.070, p < 0.001). Also, the association of insomnia severity with functional performance was partially mediated by the pace of biological aging (β = -0.105, p < 0.001). Thus, insomnia remains strongly predictive of cLBP outcomes, and the pace of biological aging helps explain this association. Future prospective studies with repeated assessments are needed to uncover the directionality of these complex relationships and ultimately develop interventions to manage cLBP.

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Section: Discussionmentioning

confidence: 99%

The pace of biological aging helps explain the association between insomnia and chronic low back pain

Aroke,

Wiggins,

Hobson

et al. 2023

Mol Pain

View full text Add to dashboard Cite

show abstract

“…In recent years, chronic BP has received much attention both in domestic [5,6,7,8] and foreign [9,10,11,12] literature. The urgency of the problem is due not only to medical, but also to social factors.…”

Section: Introductionmentioning

confidence: 99%

Application of Patient-Reported Outcomes in Back Pain in Adults: Part 2

Trefilova,

Shnayder,

Novitsky

et al. 2023

jour

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The aim of the research is generalization of information about the most common foreign and domestic scales and questionnaires used in acute and chronic back pain (BP). The analysis of Russian-language and foreign literature was carried out with a search depth of 5 years (2016–2021) in the following databases: e-Library, PubMed, Oxford Press, Clinical Keys, Springer, Elsevier, Google Scholar. To diagnose back pain and assess the characteristics of its course in dynamics, both a standardized study is used: collection of complaints, anamnesis, objective examination, assessment of neurological status, as well as valid PRO. For timely diagnosis and monitoring of the development of BP in patients with osteochondrosis of the spine, a wide range of scales and questionnaires were proposed, which we ranged into 4 groups: scales for assessing the quality of life of patients with BP; scales for assessing the characteristics of pain in BP; scales for assessing disease outcomes in BP; scales for assessing disability in BP. The second part of the thematic review presents an analysis of the advantages and disadvantages of scales for assessing pain characteristics, disease outcome and disability in patients with BP. Patient-reported outcomes assessment tools for patients with BP are popular in the world medical practice, however, it is necessary to adapt to the use in domestic clinical practice of such scales as Pain Quality Assessment Scale and Pain Quality Assessment Scale Revised (PQAS and PQAS-R), The Patient Assessment for Low Back Pain - Symptoms (PAL-S), Orebro Musculoskeletal Pain Questionnaire (OMPQ).

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Section: Introductionmentioning

confidence: 99%

Application of Patient-Reported Outcomes in Back Pain in Adults: Part 1

Trefilova¹,

Shnayder

Novitsky³

et al. 2022

jour

View full text Add to dashboard Cite

The aim of the research is generalization of information about the most common foreign and domestic scales and questionnaires used in acute and chronic back pain (BP). The analysis of Russian-language and foreign literature was carried out with a search depth of 5 years (2016–2021) in the following databases: e-Library, PubMed, Oxford Press, Clinical Keys, Springer, Elsevier, Google Scholar. For the diagnosis of acute and chronic BP and the assessment of the characteristics of its course in dynamics, both a standardized study may be use: collection of complaints, anamnesis, objective examination, assessment of neurological status, as well as valid scales and questionnaires. For the timely diagnosis and monitoring of the development of BP in patients, a wide range of scales and questionnaires were proposed, which were conventionally ranked into 4 groups: scales for assessing the quality of life of patients with BP; scales for assessing the characteristics of pain in BP; scales for assessing the outcomes of the disease in BP; scales for assessing disability in BP. The first part of the thematic review presents an analysis of the advantages and disadvantages of scales for assessing the quality of life of patients with BP. These perspective scales for assessing the quality of life of patients with BP are popular in the world neurological practice. It is necessary to adapt to the use in domestic clinical practice the Stratford Functional Back Pain Scale, the Index of Disability Associated with Pain, The Patient Assessment for Low Back Pain–Impacts.

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Practical guidelines for the treatment of chronic nonspecific low back pain and comorbid chronic insomnia: clinical observation

Cited by 12 publications

References 24 publications

The pace of biological aging helps explain the association between insomnia and chronic low back pain

The pace of biological aging helps explain the association between insomnia and chronic low back pain

Application of Patient-Reported Outcomes in Back Pain in Adults: Part 2

Application of Patient-Reported Outcomes in Back Pain in Adults: Part 1

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