2014
DOI: 10.1016/j.cgh.2013.10.005
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Practice-Owned Pathology Services: Controversies and Pitfalls—The Use of Special Stains

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Cited by 3 publications
(1 citation statement)
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“…The CAPP2 trial recruited almost 1000 people with Lynch syndrome (hereditary non-polyposis colon cancer or HNPCC), caused by a germline mutation in DNA mismatch repair (MMR) genes. 52 Lynch syndrome carriers are known to have a lifetime incidence of colorectal cancer and endometrial cancer of approximately 75% and 50%, respectively, 53 as well as increased risks of other solid tumours. Random allocation to 600 mg of aspirin for 2 years or more significantly reduced the development of colorectal cancer (HR: 0.41, 95% CI: 0.19–0.86) compared with placebo.…”
Section: Clinical Evidence Supporting the Use Of Aspirin To Prevent Gmentioning
confidence: 99%
“…The CAPP2 trial recruited almost 1000 people with Lynch syndrome (hereditary non-polyposis colon cancer or HNPCC), caused by a germline mutation in DNA mismatch repair (MMR) genes. 52 Lynch syndrome carriers are known to have a lifetime incidence of colorectal cancer and endometrial cancer of approximately 75% and 50%, respectively, 53 as well as increased risks of other solid tumours. Random allocation to 600 mg of aspirin for 2 years or more significantly reduced the development of colorectal cancer (HR: 0.41, 95% CI: 0.19–0.86) compared with placebo.…”
Section: Clinical Evidence Supporting the Use Of Aspirin To Prevent Gmentioning
confidence: 99%