Practolol and Isoprenaline in Status Asthmaticus

??-Adrenergic Receptor Blocking Drugs in Hypertension

“…Practolol has been shown to prevent the fall in arterial oxygen tension seen in asthmatic subjects after isoprenaline (Palmer et al, 1969) without diminishing significantly the bronchodilator effect of isoprenaline. The use of practolol with large doses of isoprenaline has been reported to be successful in severe status asthmaticus (Howard et al, 1972). Thus it may be advantageous for some asthmatics to take practolol; an increased dose of bronchodilator may in certain circumstances turn out to be a small price to pay if there are definite advantages to be gained from {3-blockade.…”