Pre-Disposing and Precipitating Factors in Men With Spontaneous Coronary Artery Dissection

Fahmy, Peter; Prakash, Roshan; Starovoytov, Andrew; Boone, Robert; Saw, Jacqueline

doi:10.1016/j.jcin.2016.02.024

Cited by 96 publications

(92 citation statements)

References 4 publications

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“…6,8,11,13,30,31,33,36 One study reported that men presented with SCAD at a slightly younger age than women (mean age, 48.6 [SD, 9.8] years versus 52.3 [SD, 9.2] years; P =0.05). 37,38 Although SCAD has been reported in all major racial and ethnic groups, the majority of patients are white, a finding that may reflect referral and sampling bias and the demography of patients cared for at reporting centers. 8,13,15 …”

Section: Epidemiologymentioning

confidence: 99%

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Hayes¹,

Kim²,

Saw³

et al. 2018

Circulation

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942

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Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.

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Section: Epidemiologymentioning

confidence: 99%

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Hayes¹,

Kim²,

Saw³

et al. 2018

Circulation

Self Cite

942

1,344

View full text Add to dashboard Cite

show abstract

“…In some cases however, there seems to be a significant lag time between the last exercise episode and the onset of symptoms of SCAD, suggesting high exercise capacity may be part of the phenotype of a patient with SCAD rather than a direct cause of the dissection. An association with exercise is more frequent in male SCAD cases 20. Altered coronary shear stress and vasoreactivity may also explain the rare case reports associating SCAD with cocaine,21–23 amphetamine use5 24 25 and a possible association with migraine 26…”

Section: Introductionmentioning

confidence: 99%

Spontaneous coronary artery dissection

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2017

Heart

190

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Learning objectives:• To recognise spontaneous coronary artery dissection as a cause of myocardial infarction in low risk, predominantly female, patients • To understand that although spontaneous coronary artery dissection is an important cause of peripartum myocardial infarction, ~90% of incident cases are not pregnant • To be aware that a visible dissection flap at angiography is absent in the majority of cases • To understand the rationale for an 'as conservative as possible' approach to revascularisation and key challenges in medical treatment

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“…5,12 Examples include swimming in cold lakes, downhill skiing, recent unemployment, or death of a close relative/friend. Although the association of SCAD with extreme exertion has been reported more commonly among men, 3,19 this association is also observed among women.…”

Section: Associated Conditions and Risksmentioning

confidence: 94%

Spontaneous coronary artery dissection in women: What is known and what is yet to be understood

Kok

Hayes

2018

Clinical Cardiology

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Spontaneous coronary artery dissection is a nonatherosclerotic etiology of acute coronary syndrome, including sudden cardiac death, which frequently affects younger women. This review highlights contemporary knowledge regarding spontaneous coronary artery dissection demographics, prevalence, diagnosis, presentation, and associated conditions and risks, inpatient treatment, major adverse clinical events, and outpatient management decisions.

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Pre-Disposing and Precipitating Factors in Men With Spontaneous Coronary Artery Dissection

Cited by 96 publications

References 4 publications

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Spontaneous coronary artery dissection

Spontaneous coronary artery dissection in women: What is known and what is yet to be understood

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