Pre-exposure prophylaxis (PrEP) indication and uptake among people receiving buprenorphine for the treatment of opioid use disorder

Beck, Lori; Parlier-Ahmad, Anna Beth; Martin, Caitlin E.

doi:10.1016/j.jsat.2021.108506

Cited by 9 publications

(6 citation statements)

References 23 publications

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“…Based on the prevalence of lifetime STIs and rates of condomless sex within our population, coupled with the high rates of HIV among Black Kentuckians, Black men and women who misuse opioids may benefit from HIV prevention tools such as pre-exposure prophylaxis (PrEP). Efforts to increase PrEP uptake among men and women who misuse opioids have not been as effective (Beck et al, 2022). Previous research has shown people who misuse opioids have limited awareness of PrEP, ranging from 7% to 23% (Beck et al, 2022).…”

Section: Discussionmentioning

confidence: 99%

“…Efforts to increase PrEP uptake among men and women who misuse opioids have not been as effective (Beck et al, 2022). Previous research has shown people who misuse opioids have limited awareness of PrEP, ranging from 7% to 23% (Beck et al, 2022). Thus, this population may benefit from PrEP education and access to PrEP in OUD treatment programs (Beck et al, 2022; Jones et al, 2019).…”

Section: Discussionmentioning

confidence: 99%

“…Previous research has shown people who misuse opioids have limited awareness of PrEP, ranging from 7% to 23% (Beck et al, 2022). Thus, this population may benefit from PrEP education and access to PrEP in OUD treatment programs (Beck et al, 2022; Jones et al, 2019). Increasing knowledge of PrEP and access to HIV testing can increase willingness to initiate PrEP (Ni et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

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Correlates of Transactional Sex Among Black Men and Women Who Misuse Opioids

Thorpe,

Orphé,

Pitcher

et al. 2024

Health Educ Behav

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The rise in opioid misuse coincides with increased sexually transmitted infection (STI) and HIV incidence. Transactional sex is an under-researched phenomenon among Black Americans who misuse opioids, and may increase their risk of STI or HIV transmission. Given the disproportionate impact of the opioid epidemic on Black Americans and the risks associated with opioid misuse, the current study aims to investigate sociostructural factors, history of violence, and sexual risk factors associated with transactional sex among Black men and women. A sample of n = 375 Black adult Kentuckians reporting opioid misuse completed a survey including transactional sex, sociostructural, violence history, and sexual risk measures. Results of chi-squares and independent samples t-tests revealed that compared to men who did not report engaging in transactional sex, men who engaged in transactional sex were less educated, reported being sexually assaulted or having an unwanted sexual experience in their lifetime, and were more likely to use opioids or cocaine before or during sex in the last year. Women who engaged in transactional sex had a history of violence, more structural barriers, higher psychological distress, and engaged in more sexual risk behaviors compared to women who did not engage in transactional sex. Implications for future research and interventions with this population are discussed.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Correlates of Transactional Sex Among Black Men and Women Who Misuse Opioids

Thorpe,

Orphé,

Pitcher

et al. 2024

Health Educ Behav

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“…Although oral PrEP is approved for reducing HIV transmission via injection drug use, TAF/FTC and injectable cabotegravir have not yet been evaluated for injection drug use–related risk among persons who inject drugs . However, persons who use drugs may acquire HIV via condomless sexual intercourse; therefore, if they are at sexual risk of HIV acquisition, they should be offered PrEP (evidence rating: AIa) …”

Section: Substance Use In Persons At Risk For and With Hivmentioning

confidence: 99%

Antiretroviral Drugs for Treatment and Prevention of HIV Infection in Adults

Gandhi

Bedimo

Hoy

et al. 2023

JAMA

317

148

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ImportanceRecent advances in treatment and prevention of HIV warrant updated recommendations to guide optimal practice.ObjectiveBased on a critical evaluation of new data, to provide clinicians with recommendations on use of antiretroviral drugs for the treatment and prevention of HIV, laboratory monitoring, care of people aging with HIV, substance use disorder and HIV, and new challenges in people with HIV, including COVID-19 and monkeypox virus infection.Evidence ReviewA panel of volunteer expert physician scientists were appointed to update the 2020 consensus recommendations. Relevant evidence in the literature (PubMed and Embase searches, which initially yielded 7891 unique citations, of which 834 were considered relevant) and studies presented at peer-reviewed scientific conferences between January 2020 and October 2022 were considered.FindingsInitiation of antiretroviral therapy (ART) is recommended as soon as possible after diagnosis of HIV. Barriers to care should be addressed, including ensuring access to ART and adherence support. Integrase strand transfer inhibitor–containing regimens remain the mainstay of initial therapy. For people who have achieved viral suppression with a daily oral regimen, long-acting injectable therapy with cabotegravir plus rilpivirine given as infrequently as every 2 months is now an option. Weight gain and metabolic complications have been linked to certain antiretroviral medications; novel strategies to ameliorate these complications are needed. Management of comorbidities throughout the life span is increasingly important, because people with HIV are living longer and confronting the health challenges of aging. In addition, management of substance use disorder in people with HIV requires an evidence-based, integrated approach. Options for preexposure prophylaxis include oral medications (tenofovir disoproxil fumarate or tenofovir alafenamide plus emtricitabine) and, for the first time, a long-acting injectable agent, cabotegravir. Recent global health emergencies, like the SARS-CoV-2 pandemic and monkeypox virus outbreak, continue to have a major effect on people with HIV and the delivery of services. To address these and other challenges, an equity-based approach is essential.Conclusions and RelevanceAdvances in treatment and prevention of HIV continue to improve outcomes, but challenges and opportunities remain.

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“…The available literature confirms that PWID with OUD have HIV risk behaviors, yet frequently low awareness of PrEP. This includes people who remain engaged in treatment for OUD [ 2 ]. In rural areas, participants view PrEP as a method to reduce risk of HIV for sexual encounters, and homophobia remains a barrier to uptake [ 3 ].…”

mentioning

confidence: 99%