Unmanned aerial vehicles (UAVs) are unpiloted flying robots. The term UAVs broadly encompasses drones, micro-, and nanoair/aerial vehicles. UAVs are largely made up of a main control unit, mounted with one or more fans or propulsion system to lift and push them through the air. Though initially developed and used by the military, UAVs are now used in surveillance, disaster management, firefighting, border-patrol, and courier services. In this chapter, applications of UAVs in agriculture are of particular interest with major focus on their uses in livestock and crop farming. This chapter discusses the different types of UAVs, their application in pest control, crop irrigation, health monitoring, animal mustering, geo-fencing, and other agriculture-related activities. Beyond applications, the advantages and potential benefits of UAVs in agriculture are also presented alongside discussions on business-related challenges and other open challenges that hinder the wide-spread adaptation of UAVs in agriculture.