Precision medicine: Beyond the inflection point

Abstract

PERSPECTIVEA conf uence of biological, physical, engineering, computer, and health sciences is setting the stage for a transformative leap toward data-driven, mechanism-based health and health care for each individual.

Precision Medicine: The New Frontier in Idiopathic Pulmonary Fibrosis

“…We believe precision medicine represents the new frontier for IPF clinical research, one that provides an opportunity to explore a more mechanistic, pathobiological, environmental, and behavioral approach to disease classification and treatment (8,75). If successful, precision medicinebased investigations will identify IPF subpopulations that share pathobiological pathways and target those pathways with novel mechanism-specific drugs.…”

“…A recent editorial suggested we are at an inflection point in the growth of medical science between a steady but slowing contribution from traditional approaches to clinical investigation (e.g., observation and descriptive categorization) and a new and accelerating "precision medicine"-based contribution driven by advances in molecular genomics, computational speed, and bioinformatics (8). This is an exciting and potentially revolutionary moment in medicine.…”

L’intelligence artificielle à l’aide des myologues

“…Souvent présentée comme une méde-cine sur mesure ou personnalisée adaptée à chaque patient, la médecine de précision est caractérisée par l'utilisation massive de données digitales (big data). L'analyse de ces données contribue au développement des connaissances médicales : elle guide le médecin et l'aide à améliorer les prestations de soin pour atténuer voire retarder des maladies tant au niveau individuel qu'au niveau de la population [2]. Proposé par Lee Hood, ce concept visionnaire prend en compte les caractéristiques particulières de chaque individu et est appelé médecine 4P « Personnalisée, Prédictive, Préventive et Participative » [3].…”

Applying ADDIE Model to Ideate Precision Medicine in a Polytechnic Biomedical Science Programme

“…On a similar note, promising clinical utility of precision medicine is also evident in literatures [4]. Undoubtedly, precision medicine has its transformational role in converging biomedical science, physical science, and engineering research for the promotion of health care strategies that are individual-centric, datadriven, and mechanism-based [5]. To ensure that biomedical science polytechnic students are not deficient in the emerging area of genomics in laboratory medicine, inclusion of a relevant molecular diagnostic module is inevitably necessary.…”