"Predict the relationship between pesticide genotoxicity and breast cancer risk in South Indian women  in vitro and in vivo Experiments"

Abstract

Breast cancer is the second most common cancer-related cause of death in women. BC is a multi-step process involving a range of cell types, and preventing it is still a difficult task all over the world. Agriculture is a massive industry that employs the majority of the world's population. Pesticides are a class of compounds with specific qualities that are used to remove pests. However, it occasionally exhibits severe biological activities in non-target creatures such as humans. About 504 patients and control samples were checked for pesticide levels and DNA Damage responsible for breast cancer, which is confirmed by checking the in vitro and in vivo experiments of DNA Damage. Statistical analysis was done using SPSS software. The results show positive involvement of breast cancer and pesticide risk. The relationship between pesticide and breast cancer due to DNA Damage is proved in this study. Further clinical implication of this study is to be explored to develop therapeutic approaches in treating the same.