2012
DOI: 10.2215/cjn.03020312
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Predicting Baseline Creatinine in Hospitalized Patients

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Cited by 8 publications
(10 citation statements)
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“…26 Baseline serum creatinine (SCr) before AKI was determined either by a SCr taken before, but within the preceding year of admission, or the lowest normal SCr at discharge or on follow-up. 27,28 If no baseline SCr was available, an estimated baseline SCr was calculated based on a Modification of Diet in Renal Disease (MDRD) equation estimated glomerular filtration rate (eGFR) of 75 ml/min per 1.73 m 2 . 26,29,30 …”
Section: Methodsmentioning
confidence: 99%
“…26 Baseline serum creatinine (SCr) before AKI was determined either by a SCr taken before, but within the preceding year of admission, or the lowest normal SCr at discharge or on follow-up. 27,28 If no baseline SCr was available, an estimated baseline SCr was calculated based on a Modification of Diet in Renal Disease (MDRD) equation estimated glomerular filtration rate (eGFR) of 75 ml/min per 1.73 m 2 . 26,29,30 …”
Section: Methodsmentioning
confidence: 99%
“…However, this has more to do with a lack of consensus on the best estimate for baseline creatinine in the literature. 21 Investigators have used varying surrogates for baseline SCr, including first inpatient value, minimum inpatient value, average of first 3 values, and an average of outpatient value within 1 year prior to hospitalizations. This lack of consensus makes comparisons difficult and sometimes impractical.…”
Section: Discussionmentioning
confidence: 99%
“…1 But, there is no consensus on what the baseline should be, and investigators have used different surrogates. [21][22][23] If no reliable estimate of baseline SCr can be made, the KDIGO guidelines recommend using the lowest SCr during hospitalization as the baseline. 1 Although there may be risk of dilutional artefact in SCr measurements if blood samples are drawn from an intravenous line, our hospital quality metrics indicate that test cancellations due to "improper collection" are rare.…”
Section: Acute Kidney Injury Criteria and Baseline Creatininementioning
confidence: 99%
“…However, the baseline SCr identification method had not been well‐described in the modern literature. Because the definition for baseline SCr is not standardized, this can lead to heterogeneity across studies and potentially misclassify the kidney function in hospitalized and ICU patients …”
Section: Discussionmentioning
confidence: 99%
“…Studies have shown that outpatient SCr is a more robust assessment of baseline renal function than inpatient SCr, because it represents a steady state and is not altered by the index critical illness . However, there is currently no consensus on how to optimally determine baseline SCr when multiple preadmission SCr measurements are available, leading to heterogeneity across research studies …”
mentioning
confidence: 99%