Predicting early mortality in acute exacerbation of chronic obstructive pulmonary disease using the CURB65 score

Abstract

A simple 6-point score based on confusion, blood urea, respiratory rate, blood pressure and age can be used to stratify patients with COPD exacerbation into different management groups. The CURB65 score was as effective in predicting early mortality in our cohort of acute COPD exacerbations as it was in previous cohorts with community acquired pneumonia. Our findings suggest that CURB65 scores can help clinicians to assess patients with exacerbation of COPD.

Clinical characteristics associated with adverse events in patients with exacerbation of chronic obstructive pulmonary disease: a prospective cohort study

“…25 Other prospective studies conducted only after admission to hospital have been limited by similar concerns, and most of these attempted only to predict mortality. [26][27][28][29][30] Others involved retrospective analyses of existing databases, were focused on inpatients or mortality, and were not directly applicable to the emergency department. [31][32][33][34][35] Strengths and limitations Our study had several strengths, including multi centre and rigorous prospective collection of real-time clinical data, comprehensive followup and unique use of the 3-minute walk test.…”

Detailed Characterization of Hospitalized COPD Patients in Relation to Combined COPD Assessment by GOLD

“…These are recognized prognostic indicators of respiratory distress and failure [26,27]. Interestingly, arterial pO 2 was associated with increased likelihood of hospital mortality from the simple logistic regression.…”

A Computer Application to Predict Adverse Events in the Short-Term Evolution of Patients With Exacerbation of Chronic Obstructive Pulmonary Disease (Preprint)

“…Some of them have been translated into clinical prediction rules or scores for predicting short-term outcomes or stratifying patients based on their probability of adverse evolution [18,[24][25]. However, as far as we know, none of them has been incorporated on an available and easy to use computer application that only needs to be downloaded to a computer device, such as a tablet or smartphone, in order to be used.…”