“…All except one study (Chase, et al, 2000) showed that children with HIV infection received ARVs according to accepted guidelines (at the time of data collection) on the standard of care for paediatric HIV patients (Rice, et al, 2012;Koekkoek, et al, 2008;Lindsey, et al, 2007;Foster, et al, 2006;Nozyce, et al, 2006;Smith, et al, 2006;Llorente, et al, 2003;Macmillan, et al, 2003;Blanchette, et al, 2001;Pearson, et al, 2000;Smith, et al, 2000). The advancements in pharmacological management during the data collection period of these studies introduced error which could not be controlled.…”