2020
DOI: 10.1007/s00431-020-03847-6
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Predicting nasal high-flow therapy failure by pediatric respiratory rate-oxygenation index and pediatric respiratory rate-oxygenation index variation in children

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Cited by 38 publications
(38 citation statements)
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“…The authors found that a higher ROX index score was associated with HFNC success at all time points analyzed, and they concluded that a ROX index value of ≥ 4.88 at 12 h after the initiation of HFNC therapy was significantly associated with HFNC success. However, in children, predicting success using the ROX index can be much more difficult, because the respiratory rate can vary with age (27). In our study, there were no significant differences in initial and lowest ROX index scores between the two groups.…”
Section: The Risk Factors For Escalation Of Therapy With the Use Of Hfnc Therapycontrasting
confidence: 56%
“…The authors found that a higher ROX index score was associated with HFNC success at all time points analyzed, and they concluded that a ROX index value of ≥ 4.88 at 12 h after the initiation of HFNC therapy was significantly associated with HFNC success. However, in children, predicting success using the ROX index can be much more difficult, because the respiratory rate can vary with age (27). In our study, there were no significant differences in initial and lowest ROX index scores between the two groups.…”
Section: The Risk Factors For Escalation Of Therapy With the Use Of Hfnc Therapycontrasting
confidence: 56%
“…No se encontraron diferencias en la tasa de IOT y la mortalidad entre la CNAF y la oxigenoterapia estándar o CPAP. Estos resultados ayudan a mantener abierta la controversia acerca de las incertidumbres que aun rodean las indicaciones, grupos de edad, comorbilidades y gravedad de la dificultad respiratoria que debe ser considerada al seleccionar los pacientes candidatos a oxigenoterapia con CNAF fuera del ámbito de UCIP (22)(23)(24).…”
Section: Resultsunclassified
“…ROX index, defined as the ratio of SpO 2 /FiO 2 to respiratory rate, has been reported to have a high predictive value to identify HFNC failure in critically ill patients with acute hypoxemic respiratory failure (AHRF) ( 35 ). A study published 2 years later discovered that combining pediatric ROX index (p-ROXI) and its dynamic alterations can successfully predict HFNC failure within 24 h and 48 h of therapy onset ( 36 ). However, the respiratory rate z-score, instead of respiratory rate, is not routinely used clinically and is cumbersome and decreased the value as a bedside monitoring indicator.…”
Section: Discussionmentioning
confidence: 99%