Predictive factors for local recurrence after glansectomy and neoglans reconstruction for penile squamous cell carcinoma

Penile cancer: a Brazilian consensus statement for low- and middle-income countries

“…Therefore, patients presenting with Tis, Ta, and T1 G1-3 disease may benefit from conservative treatment. However, they have a higher risk of local recurrence, and physicians must closely monitor these patients through follow-up, especially when presenting perineural invasion, Tis, positive definitive margins, and high-grade tumors (Albersen et al 2018 ). Besides, organ-sparing surgery does not provide a significant difference in overall survival compared with total or partial penectomy (Lindner et al 2019 ; Djajadiningrat et al 2014a , b ).…”

Management of penile cancer patients during the COVID-19 pandemic: An eUROGEN accelerated Delphi consensus study

“…Although penile-preserving surgery (i.e., glansectomy with skin-grafting) increases patients’ quality of life based on preservation of penile length, it requires a longer operating time and the need for general anesthesia. Furthermore, procedures requiring skin grafting have an inherent risk for complications such as graft loss or infection, which can increase the length of hospitalization and readmission rates [6] . Thus, the panel proposed that glansectomy and partial penectomy should be performed under LA, whenever possible, for T2 and T3 lesions, and to avoid reconstruction with skin grafting.…”

“…Consensus achievement was defined as attaining ≥80% agreement on each question based on previous studies [17] . The survey was subdivided into 4 sections with 82 questions overall relevant to a particular theme: General questions (4 questions), environment [6] , patients (63), and healthcare workforce [11] .…”

“…Delaying penile cancer treatment can lead to disease progression of the primary tumor [ 4 , 5 ] such that organ-sparing surgery may no longer be feasible [6] ; similarly, the development of metastatic disease in the inguinal lymph nodes has an impact on cancer specific survival [7] , [8] , [9] , [10] . To mitigate the health risks to patients because of the reconfiguration of services during the COVID-19 pandemic, prioritization of patients with time-critical cancers has been proposed [11] .…”

Recent advances in the management of penile cancer

“…These include perineural invasion, carcinoma in situ , positive margins and high-grade disease. This in turn allows tailored follow-up for patients with PC, improving the overall quality of their care 32 .…”