Predictive value of inter-atrial block for new onset or recurrent atrial fibrillation: A systematic review and meta-analysis

Tse, Gary; Wong, Cheuk Wai; Gong, Mengqi; Wong, Wing Tak; Bazoukis, George; Wong, Sunny H.; Li, Guangping; Wu, William Ka Kei; Tse, Lap Ah; Λαμπρόπουλος, Κωνσταντίνος; Xia, Yunlong; Liu, Tong; Baranchuk, Adrián

doi:10.1016/j.ijcard.2017.09.176

Cited by 87 publications

(70 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…First, advanced IAB is likely a presentation of AP‐independent atrial electrophysiological abnormalities that remain after successful AP ablation. In support of this, advanced IAB was previously reported to reflect the underlying atrial substrate with atrial fibrosis and to be associated with the development of AF . Second, advanced IAB may play a role in initiating and maintaining reentry circuits by promoting the occurrence of unidirectional block, an important mechanism in the development of AF.…”

Section: Discussionmentioning

confidence: 66%

“…In support of this, advanced IAB was previously reported to reflect the underlying atrial substrate with atrial fibrosis 27,28 and to be associated with the development of AF. [12][13][14][15][16][17][18][19][20] Second, advanced IAB may play a role in initiating and maintaining reentry circuits by promoting the occurrence of unidirectional block, 29 an important mechanism in the development of Multiple APs, n (%) 5 (4.9%) 0 (0.0%) 5 (5.4%) 1.00…”

Section: Discussionmentioning

confidence: 99%

“…10 The appearance of advanced IAB is frequently associated with atrial tachyarrhythmias, and has been found to predict AF in multiple clinical scenarios. [12][13][14][15][16][17][18][19][20] However, the role of advanced IAB in predicting the recurrence of AF after AP ablation in patients with WPW syndrome is unclear. Thus, in the present study, we investigated the clinical utility of advanced IAB for predicting the risk of AF recurrence in patients with verified paroxysmal AF and WPW syndrome after successful AP ablation.…”

Section: Paroxysmal Atrial Fibrillation (Af) Occurs Frequently In Patmentioning

confidence: 99%

“…A prolonged P‐wave with biphasic (±) morphology in the inferior leads represents an even higher degree of IAB and has been referred to as advanced IAB . The appearance of advanced IAB is frequently associated with atrial tachyarrhythmias, and has been found to predict AF in multiple clinical scenarios . However, the role of advanced IAB in predicting the recurrence of AF after AP ablation in patients with WPW syndrome is unclear.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Advanced interatrial block predicts recurrence of atrial fibrillation after accessory pathway ablation in patients with Wolff‐Parkinson‐White syndrome

Zhao

et al. 2019

Clinical Cardiology

View full text Add to dashboard Cite

Background Paroxysmal atrial fibrillation (AF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Although successful ablation of the accessory pathway (AP) eliminates paroxysmal AF in some patients, in other patients it can recur. Hypothesis We investigated the clinical utility of advanced interatrial block (IAB) for predicting the risk of AF recurrence in patients with verified paroxysmal AF and WPW syndrome after successful AP ablation. Methods This retrospective study included 103 patients (70 men, 33 women; mean age, 44 ± 16 years) with WPW syndrome who had paroxysmal AF. A resting 12‐lead electrocardiogram was performed immediately after successful AP ablation to evaluate the presence of advanced IAB, which was defined as a P‐wave duration of >120 ms and biphasic [±] morphology in the inferior leads. Results During the mean follow‐up period of 30.9 ± 20.0 months (range, 2‐71 months), 16 patients (15.5%) developed AF recurrence. Patients with advanced IAB had significantly reduced event‐free survival from AF ( P < .001). Cox regression analysis with adjustment for the left atrial diameter and CHA 2 DS 2 ‐VASc score identified advanced IAB (hazard ratio, 9.18; 95% confidence interval [CI], 2.30‐36.72; P = .002) and age > 50 years (hazard ratio, 12.64; 95% CI, 1.33‐119.75; P = .027) as independent predictors of AF recurrence. Conclusions Advanced IAB was an independent predictor of AF recurrence after successful AP ablation in patients with WPW syndrome.

show abstract

Section: Discussionmentioning

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Paroxysmal Atrial Fibrillation (Af) Occurs Frequently In Patmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Advanced interatrial block predicts recurrence of atrial fibrillation after accessory pathway ablation in patients with Wolff‐Parkinson‐White syndrome

Zhao

et al. 2019

Clinical Cardiology

View full text Add to dashboard Cite

show abstract

“…Advanced IAB (a‐IAB) presents biphasic morphology in the inferior leads (II, III, aVF) while partial IAB (p‐IAB) does not present a negative component in the inferior leads. Recently, several studies identified IAB as a reliable predictor for new onset of atrial fibrillation (AF), AF recurrences following pulmonary vein isolation and pharmacological cardioversion and increased risk of ischemic stroke …”

Section: Introductionmentioning

confidence: 99%