Predictors of functional decline in locally advanced head and neck cancer patients from South Brazil

Silver, Heidi J.; Guimaraes, Christine de Campos Graf; Pedruzzi, P.A.G.; Badia, Maraisa; Carvalho, Adriana Spuldaro de; Oliveira, Benedito Valdecir de; Ramos, Gyl Henrique Albrecht; Dietrich, Mary S.; Pietrobon, Ricardo

doi:10.1002/hed.21322

Cited by 19 publications

(17 citation statements)

References 44 publications

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“…29 In the present study, a high prevalence of white skin individuals (90.04%) was observed, similar to the findings from a study conducted recently in the southern states of Brazil 30 and the Midwest of the United States. 31 However, Hayat et al 32 observed a higher prevalence of head and neck cancer among AfricanAmerican descendants from different areas of the United States.…”

supporting

confidence: 92%

Clinical and epidemiological characteristics of patients in the head and neck surgery department of a university hospital

Ruback¹,

Galbiatti²,

Arantes³

et al. 2012

Sao Paulo Med. J.

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CONTEXT AND OBJECTIVES: Head and neck cancer is the fifth most common type of cancer worldwide. The objective of this study was to evaluate the clinical and epidemiological parameters in a head and neck surgery service. DESIGN AND SETTING: Cross-sectional study using patients' records, developed in otolaryngology and head and neck department of a university hospital in the northwest of the state of São Paulo. METHODS: A total of 995 patients in the head and neck surgery service between January 2000 and May 2010 were evaluated. The variables analyzed included: age, gender, skin color, tobacco and alcohol consumption, primary site, staging and histological tumor type, treatment and number of deaths. RESULTS:The disease was more frequent among men (79.70%), smokers (75.15%) and alcohol abusers (58.25%). The most representative sites were oral cavity (29.65%) and larynx (24.12%) for the primary site; squamous cell carcinoma (84.92%) was the most frequent histological type, and surgery (29.04%) and radiotherapy (14.19%) were the most common treatments. CONCLUSION: The cancer that affects patients assisted by the head and neck surgery service occurs mainly men, smokers and alcohol abusers, and the oral cavity and larynx are the sites with the highest incidence. The high rate of patients with stages III and IV indicates late diagnosis by the treatment centers, which reflects the need for prevention education campaigns for early diagnosis of the disease. RESUMO

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supporting

confidence: 92%

Clinical and epidemiological characteristics of patients in the head and neck surgery department of a university hospital

Ruback¹,

Galbiatti²,

Arantes³

et al. 2012

Sao Paulo Med. J.

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“…In a large cohort of older people, Ahacic et al have demonstrated that fatigue was independently related to activity limitations . Furthermore, fatigue has a negative impact on daily living activities also in the setting of chronic diseases .…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Severity of Postdialysis Fatigue Are Higher in Patients on Chronic Hemodialysis With Functional Disability

et al. 2018

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The aim of the present study was to determine the intensity, duration, frequency and prevalence of postdialysis fatigue (PDF) in patients on chronic hemodialysis (PCD) with and without functional disability. Patients underwent assessment of functional ability by the Katz ADL (activity daily living) questionnaire and the Lawton and Brody scale for the instrumental activity daily living (IADL) fatigue using the SF-36 Vitality Subscale, comorbidity through the Charlson comorbidity score index (CDI), and time of recovery after hemodialysis (TIRD). We studied 271 PCD. ADL and IADL disabilities were present in 75 (27.6%) and 168 (62%) patients, respectively. Patients with ADL disability were significantly older and showed higher CDI scores, and lower levels of serum albumin and Kt/V. Prevalence of PDF was significantly higher in patients with ADL disability as well as its severity, intensity, duration and frequency. Patients with IADL disability were significantly older, had a higher CCI score, had lower levels of serum albumin and Kt/V, and had a higher severity, intensity, duration and frequency of PDF. At multivariate regression analysis, ADL disability was positively associated with age, prevalence and severity of PDF, and dialysate temperature and inversely associated with serum albumin levels. IADL disability was instead positively associated with age and dialysate temperature and inversely associated with serum albumin levels. In conclusion, prevalence and severity of PDF are significantly higher in PCD with ADL disability than in those without it. This knowledge may have important implications for the development of interventions to reduce PDF in PCD.

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“…Horiot reported that older patients may suffer from a more important functional impact, and may therefore be more vulnerable to the secondary effects of the treatment (Horiot 2007). The need for assistance with IADLs and ADLs respectively doubled and quadrupled in a vulnerable elderly H&N cancer population 6 months after treatment start, with fatigue as a predictive factor for IADL deterioration (Silver et al 2010). Likewise, in our study, self-reported fatigue was found to be significantly more present in vulnerable patients at both time points, and significantly worsened in both groups.…”

Section: Discussionmentioning

confidence: 99%

Serial comprehensive geriatric assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life

Pottel

Lycke

Boterberg

et al. 2014

Eur J Cancer Care (Engl)

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Predictors of functional decline in locally advanced head and neck cancer patients from South Brazil

Cited by 19 publications

References 44 publications

Clinical and epidemiological characteristics of patients in the head and neck surgery department of a university hospital

Clinical and epidemiological characteristics of patients in the head and neck surgery department of a university hospital

Prevalence and Severity of Postdialysis Fatigue Are Higher in Patients on Chronic Hemodialysis With Functional Disability

Serial comprehensive geriatric assessment in elderly head and neck cancer patients undergoing curative radiotherapy identifies evolution of multidimensional health problems and is indicative of quality of life

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