Predisposing Factors Associated With Chronic and Recurrent Rhinosinusitis in Childhood

Abstract

PurposeThere is currently no information regarding predisposing factors for chronic and recurrent rhinosinusitis (RS), although these are considered to be multifactorial in origin, and allergic diseases contribute to their pathogenesis. We evaluated the predisposing factors that may be associated with chronic and recurrent RS.MethodsIn this prospective study, we examined patients with RS younger than 13 years of age, diagnosed with RS at six tertiary referral hospitals in Korea between October and December, 2006. Demographic and clinical data related to RS were recorded and analyzed.ResultsIn total, 296 patients were recruited. Acute RS was the most frequent type: 56.4% of the patients had acute RS. The prevalences of other types of RS, in descending order, were chronic RS (18.9%), subacute RS (13.2%), and recurrent RS (11.5%). Factors associated with recurrent RS were similar to those of chronic RS. Patients with chronic and recurrent RS were significantly older than those with acute and subacute RS. The prevalences of allergic rhinitis, atopy, and asthma were significantly higher in patients with chronic and recurrent RS than those with acute and subacute RS.ConclusionsAn association between atopy and chronic/recurrent RS, compared to acute and subacute RS, suggests a possible causal link.

Aktueller Stand der endonasalen Nasennebenhöhlenchirurgie

“…), ▶ sehr ausgeprägte Symptome und/oder ▶ lange Erkrankungsdauer im Einzelfall. Ein enges Siebbein, das Vorhandensein infraorbitaler Zellen[201] oder eine allergische Rhinitis[620] begünstigen das Auftreten der RARS. Ziel einer Operation ist die Beseitigung von Drainagehindernissen im betroffenen Nasennebenhöhlensegment unter Erhalt der marginalen Schleimhaut, die im Intervall unauffällig ist.…”

Systematic investigation for underlying causes of recurrent infections in children: surveillance of primary immunodeficiency

“…This range of infectious events depends on many predisposing factors (2,8). The most important promoting elements are age, exposure to other children in school or daycare units (9,10), passive smoking, inadequate nutrition, living in an air-polluted area, atopy, anatomical defects and other chronic underlying disorders (11). Therefore, a challenge exists for practitioners to verify the abnormal pattern and unusual type of the infection (12), and to make a decision about the necessity of further evaluation for finding more serious underlying conditions such as immunodeficiency (13)(14)(15).…”

Clinical characteristics of recurrent acute rhinosinusitis in children

“…13 RARS is uncommon in healthy children; thus, underlying conditions including allergic rhinitis (AR), non-allergic rhinitis (NAR), immunodeficiency, ciliary dysfunction, and anatomical abnormalities of the osteomeatal complex including septal deviation, nasal polyps and concha bullosa should be investigated. 2,14,15 Currently, there are limited data on the characteristics of RARS and no treatment options have been systematically evaluated for the prevention of RARS in children. In this study, we evaluated the clinical characteristics, predisposing factors and preventive therapy of RARS in children at the Paediatric Allergy Clinic, Siriraj Hospital, Mahidol University.…”