Predisposing factors for seroma formation in patients undergoing thyroidectomy: Cross-sectional study

Abstract

IntroductionSeroma is defined as collection of fluid within the surgical site during postoperative period that causes several complications. Recognition of predisposing risk factors can lead to avoid seroma formation after thyroidectomy.Materials and methodsA cross-sectional study was carried out during a 3-year period and 678 patients were enrolled the study. We recorded demographic data, past medical history and the type of thyroidectomy were for all patients. We measured total and ionized serum calcium and albumin level in all patients before surgery and a day after it. All patients underwent total or subtotal thyroidectomy and if needed central neck dissection was performed subsequently. Patients underwent serial aspiration If they had seroma formation.ResultsThe overall post-thyroidectomy seroma incidence was 2.2%. There was no statistically significant correlation while evaluating gender, age and body mass index with post-operative seroma formation. However, seroma formation was significantly higher in patients underwent total thyroidectomy (P = 0.041). The results of postoperative laboratory tests showed a significant lower level of ionized calcium in patients with seroma formation (P < 0.0001). Logistic regression showed statistically significant value for variables including age, BMI and decreased ionized calcium level, in developing of seroma.ConclusionWe showed that Seroma formation was lower during thyroidectomy via electrical vessel sealing system in comparison with previous studies. In our study, older age, greater body mass index and decreased ionized calcium level were predictors of seroma formation.

Transaxillary gasless endoscopic thyroidectomy versus conventional open thyroidectomy: systematic review and meta-analysis.

“…The bleeding rate after open and endoscopic techniques varies from 0.36% to 4.3% [ 33 ]. Seroma formation subsequent to thyroid surgery varies from 1.3% to 7% [ 34 ]. The results of our meta-analysis showed no significant differences in postoperative bleeding and seroma formation in transaxillary thyroidectomy versus open thyroidectomy.…”

Indications and complications of thyroidectomy in Al-Ramadi teaching hospital

“…However, the prior meta-analysis study [25] concluded that there were no statistically significant differences in the incidence of neck hematoma/seroma in those with usage of drains or those without drains. In a recent study reported that increasing age of the patient, high body mass index, and low level of ionized calcium are a predisposing factor for seroma formation [26]. Stitch granuloma was observed in one patient and we found that the suture material used was catgut as this suture causes considerable inflammatory reaction .…”

Parathyroid hormone level after total thyroidectomy using conventional versus harmonic focus technique: Prospective randomized study

“…Dehal and colleagues investigated 147,344 thyroid and parathyroid procedures and reported a hematoma in the neck was found in 1.5 percent [ 22 ]. Ramouz et al found that 70 of 6,830 hematomas required exploration in a large case-controlled study, accounting for 1.02 percent of all hematomas and found no significant difference in postoperative hematoma formation between the Ligasure small jaw and Harmonic scalpel groups [ 23 ].…”