Preeclampsia in Jordan: incidence, risk factors, and its associated maternal and neonatal outcomes

Khader, Yousef; Batieha, Anwar; Al-Njadat, Rania Ali; Hijazi, Sa'ad

doi:10.1080/14767058.2017.1297411

Cited by 56 publications

(71 citation statements)

References 20 publications

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“…In addition to the family history of PE, the logistic regression analysis showed that primiparous women present an increased risk of nineteen times to develop PE when compared to women with more than two pregnancies. These results are similar to those by Khader et al, 18 observed that women in Jordanian had a twice the increased risk in developing PE in the first pregnancy than in later ones. Hernandez-Dias et al 19 also showed that multiparous women with no history of PE had a 1% risk of developing the disease, while women with PE in one or two consecutive pregnancies presented a 15-30% risk of recurrence, respectively.…”

Section: Discussionsupporting

confidence: 92%

Investigation of rs1800469 and rs1800468 Polymorphisms of the TGF-β1 Gene in Women with Pre-eclampsia

Hortolani

Tanaka

Paschoini

et al. 2018

Rev. Bras. Saude Mater. Infant.

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Objectives: to verify the contribution of polymorphisms rs1800469 and rs1800468 of the TGF-β1 gene and the risk factors for the pre-eclampsia development.Methods: this is a case-control study with 257 women from the Uberaba region of Minas Gerais were selected, 88 of them were in the pre-eclampsia group and 169 in the control group. Genotyping was performed by allelic discrimination using the real-time PCR technique. The odds ratio and the 95% confidence interval were used to evaluate the probability of the polymorphisms studied contributing for the pre-eclampsia development. The logistic regression analysis was performed to evaluate the relation among family recurrence, smoking, primiparity and the presence of polymorphic alleles and susceptibility of preeclampsia.Results: no association was found between polymorphisms rs1800469 and rs1800468 of the TGF-β1 gene and pre-eclampsia. The logistic regression analysis was statistically significant for family recurrence, showing that women with a family history of pre-eclampsia and primiparity are at an increased risk of developing the disease.Conclusions: no association was found between polymorphisms rs1800469 and rs1800468 of the TGF-β1 and pre-eclampsia gene. Factors such as family history and primiparity were associated to the risk of developing pre-eclampsia. 184Cancian-Hortolani AC et al.

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Section: Discussionsupporting

confidence: 92%

Investigation of rs1800469 and rs1800468 Polymorphisms of the TGF-β1 Gene in Women with Pre-eclampsia

Hortolani

Tanaka

Paschoini

et al. 2018

Rev. Bras. Saude Mater. Infant.

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“…In their study, Khader et al (22) reported that the incidence of preeclampsia was high in pregnant women with a gestational age of ≤31 weeks. In our study, we found that the gestational week was lower in the HDP group than the control group and that the low gestational week was a risk factor for preeclampsia.…”

Section: Discussionmentioning

confidence: 97%

“…We could not find any literature examining the relationship between gravida and preeclampsia. In most of the studies in the literature, parity and primiparity-multiparity status were examined for preeclampsia (1,10,13,21,22). The fact that patients with high gravida are older, and the possibility of comorbidity increases with older age may cause preeclampsia to be seen more frequently in this patient group.…”

Section: Discussionmentioning

confidence: 99%

Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?

Uzundere¹,

Kaçar²,

Andan³

et al. 2020

Istanbul Med J

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Amaç: Çalışmamızın öncelikli amacı gebeliğin hipertansif hastalıkları (GHH) ile kan grupları arasındaki ilişkiyi incelemektir. İkincil amacımız ise GHH'lerin gelişiminde rol oynayan risk faktörlerini belirlemektir. Yöntemler: Kesitsel, gözlemsel ve prospektif olarak planlanan çalışmamıza 15-49 yaş arası gebeler dahil edildi. Gebeler iki gruba ayrıldı. Grup 1 (n=266), GHH nedeniyle yoğun bakım ünitesine kabul ettiğimiz hastalar; grup 2 (n=402), gebelik süresince herhangi bir komplikasyon gelişmeyen ve normotansif olan hastalardan oluştu. Gruplar yaş, kan grupları, Rh faktörü, gravida, parite, gebelik haftası ve primiparitemultiparite açısından karşılaştırıldı. Bulgular: Gruplar arasında ABO kan grubu ve Rh faktörü açısından istatistiksel olarak anlamlı bir fark saptanmadı. Grup 1'in yaş, gravida ve parite ortalaması grup 2'ye göre istatistiksel olarak anlamlı bir şekilde daha yüksek saptanırken (sırasıyla, p=0,028; 0,001; 0,004), gebelik haftası ortalaması grup 2'ye göre daha düşük idi (p<0,001). Ayrıca yüksek gravida, düşük gebelik haftası, komorbidite varlığı ve primiparitenin GHH için risk faktörleri olduğunu saptadık. Sonuç: Çalışmamızda GHH ile kan grupları arasında herhangi bir ilişki saptamadık. Yüksek gravida, düşük gebelik haftası, komorbidite varlığı ve primiparitenin GHH için risk faktörleri olduğunu gösterdik. Anahtar Kelimeler: ABO kan grubu, Rh faktörü, gebeliğin hipertansif hastalıkları, risk faktörleri Introduction: The primary aim of our study was to investigate the relationship between hypertensive diseases of pregnancy (HDP) and blood groups. Our secondary aim is to determine the risk factors that play a role in the development of HDP. Methods: Pregnant women aged 15-49 years were included in this cross-sectional, observational, and prospective study. Pregnant women were divided into two groups. Group 1 (n=266) included patients admitted to the intensive care unit due to HDP. Group 2 (n=402) included normotensive patients without any complications during pregnancy. The groups were compared in terms of age, blood groups, Rh factor, gravida, parity, gestational week, and primiparity-multiparity. Results: There was no statistically significant difference between the groups in terms of ABO blood group and Rh factor. The mean age, gravida, and parity were significantly higher in Group 1 than in Group 2 (p=0.028; 0.001; 0.004, respectively), while mean gestational age was lower than Group 2 (p<0.001). We also found that high gravida, low gestational age, presence of comorbidity, and primiparity were risk factors for HDP. Conclusion: We did not find any relationship between HDP and blood groups. We found that high gravida, low gestational age, presence of comorbidity, and primiparity are risk factors for HDP.

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“…En cuanto a la culminación de parto, el 97,8 % de los partos de las preelampticas fueron por cesáreas de emergencia (OR: 43,13, CI 95 %: 22,52 -84,56 y p < 0,001), dicho resultado es semejante a lo encontrado por Suarez (8). La cesárea se utilizó con mayor frecuencia entre las pacientes con preeclampsia en el 59,3 %, además representaron 5.5 más probabilidades de presentar parto pre término en el estudio de García (14).…”

Section: Discussionunclassified

Resultados maternos y perinatales de preeclampsia en el Hospital Hipólito Unanue de Tacna

Zaga

Rendón

Mamani

2020

RMB

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La preeclampsia constituye una de las principales causas de mortalidad materna y perinatal. Objetivo: Determinar los resultados maternos y perinatales de la preeclampsia. Material y métodos: Estudio analítico de casos y controles, se incluyó a todas las madres cuyos partos fueron atendidos en el Hospital Hipólito Unanue de Tacna durante los años 2014 a 2018, los datos se obtuvieron del Sistema Informático Perinatal. Se comparó los casos con los controles mediante frecuencias absolutas y relativas. Se utilizó el estadígrafo Chi2, considerando asociación significativa cuando el “p” sea menor de 0,05. Para la determinación de resultados maternos y perinatales adversos se utilizó el Odds Ratio con intervalo de confianza al 95 %, considerando riesgo significativo cuando el intervalo de confianza esté por encima de 1. Resultados: La incidencia de gestantes con preeclampsia fue de 2,8 %. Los resultados maternos asociados a la preeclampsia fueron: desprendimiento prematuro de placenta (OR = 6,41), terminación por cesárea (OR = 43,13) y muerte materna (OR = 11,60). Los resultados perinatales fueron: prematuridad (OR = 9,63), pequeños para la edad gestacional (OR = 3,80), Apgar al primer minuto de 4 a 6 (OR = 2,51), Apgar a los 5 minutos de 0 a 3 (OR = 6,29), hipoglicemia (OR = 2,65) y mortalidad perinatal (OR = 3,94) en comparación con los recién nacidos de madres sin preeclampsia. Conclusiones: La preeclampsia se asocia a mayor morbilidad y mortalidad materna y perinatal.

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Preeclampsia in Jordan: incidence, risk factors, and its associated maternal and neonatal outcomes

Abstract: The overall incidence rate of preeclampsia was 1.3%. Preeclampsia was significantly associated with maternal and neonatal morbidity and mortality as well as increasing vaginal operative delivery, cesarean section, LBW, and birth asphyxia.

Cited by 56 publications

References 20 publications

Investigation of rs1800469 and rs1800468 Polymorphisms of the TGF-β1 Gene in Women with Pre-eclampsia

Investigation of rs1800469 and rs1800468 Polymorphisms of the TGF-β1 Gene in Women with Pre-eclampsia

Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?

Resultados maternos y perinatales de preeclampsia en el Hospital Hipólito Unanue de Tacna

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