Preemptive Dexamethasone and Etoricoxib for Pain and Discomfort Prevention After Periodontal Surgery: A Double‐Masked, Crossover, Controlled Clinical Trial

Abstract

The adoption of a preemptive medication protocol using etoricoxib or dexamethasone may be considered effective for pain and discomfort prevention after open-flap debridement surgeries.

Comparison Between Dexamethasone and Ibuprofen for Postoperative Pain Prevention and Control After Surgical Implant Placement: A Double‐Masked, Parallel‐Group, Placebo‐Controlled Randomized Clinical Trial

“…Males were the majority in all groups, and men tend to report less pain than women 19 . Individuals receiving placebo were older than those receiving ibuprofen; however, some previous studies failed to correlate age with pain intensity 9 , 19 . Surgery duration was lower in the placebo group, although pain intensity was significantly higher in this group than in other groups.…”

“…Despite randomization, some differences among groups should be noted. Males were the majority in all groups, and men tend to report less pain than women 19 . Individuals receiving placebo were older than those receiving ibuprofen; however, some previous studies failed to correlate age with pain intensity 9 , 19 .…”

“…For postoperative pain, different protocols have been used to eliminate or at least minimize it 12–15 . These protocols include use of systemic medications, such as steroidal or non‐steroidal anti‐inflammatory drugs (NSAIDs) 4,16‐19 …”

“…Dexamethasone is a potent synthetic SAID that has significant benefit in controlling pain, swelling, and inflammation after third molar extraction surgeries, 20 , 21 periodontal surgeries, 4,16‐19,22 and endodontic treatment 23 , 24 . Dexamethasone acts by suppressing disruption of the arachidonic‐acid cascade.…”

Preemptive and Postoperative Medication Protocols for Root Coverage Combined with Connective Tissue Graft

“…For all of these evaluated aspects, no differences were observed between the SAID and NSAID groups, confirming the homogeneity of experimental groups and supporting the outcomes obtained in the study. These assessments were not carried out in other studies (16,17,(25)(26)(27)30), which could affect the interpretation of individual morbidity data.…”