The special issue "A Synthesis of Systematic Review Research on Emerging Learning Environments and Technologies" edited by Drs. Florence Martin, Vanessa Dennen, and Curtis Bonk has assembled a noteworthy collection of systematic review articles, each focusing on a different aspect of emerging learning technologies. In this conclusion, we focus on these evidence-based reviews and their practical implications for practitioners as well as future researchers. While recognizing the merits of these reviews, we conclude our analysis by encouraging readers to consider conducting educational design research to address serious problems related to teaching, learning, and performance, collaborating more closely with teachers, administrators, and other practitioners in tackling these problems, and always striving to make a difference in the lives of learners around the world.