Preferential crystallization in an unusual case of conglomerate with partial solid solutions

Preparative resolution of (±)-trans-1,2-diaminocyclohexane by means of preferential crystallization of its citrate monohydrate

“…13 The resolution of the structure shows that the water molecule is strongly linked to the two acidbasic functions via high energy electrostatic bonds. TG/DSC/MS experiments confirm the high degree of stability of the salt, in which dehydration occurs only at 163°C.…”

Spotting Conglomerates by Second Harmonic Generation

“…However, the detection of partial solid solutions can be of interest since some of them can be potentially adequate for preferential crystallization. 31 Considering all these situations, the SHG test is consequently proposed as a prescreening method only.…”

Recrystallization of Enantiomers from Conglomerates

“…The influence of the degree of disorder (or pseudo-symmetry) of the structure is difficult to www.intechopen.com establish so as the consequences on the  (2) coefficients. However, the detection of partial solid solutions can be of interest since some of them can be potentially adequate for preferential crystallization (Wermester et al, 2007).…”

“…Considering these elements, the perfect match of the XRPD patterns is surely the most dependable way to conclude on the conglomerate nature of a sample. XRPD is of particular interest as it also permits to check the crystallinity of the sample and to spot partial or total solid solutions (Wermester et al, 2007;Renou et al, 2007). Moreover, if a single crystal of sufficient size is available, a structure can be resolved by single crystal X-Ray diffraction.…”