Preferred Retinal Locus Locations in Age-Related Macular Degeneration

Erbezci, Murat; Öztürk, Taylan

doi:10.1097/iae.0000000000001897

Cited by 21 publications

(24 citation statements)

References 20 publications

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“…Sunness et al described a series of patients in which 90 per cent of Stargardt disease patients had loci in the inferior field and 63 per cent of patients with age‐related macular degeneration had a left field fixation locus. In another series, 29.2 per cent were nasal followed by temporal, superior and inferior . This series showed preference for superior locus.…”

Section: Discussionmentioning

confidence: 83%

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Visual rehabilitation using microperimetric acoustic biofeedback training in individuals with central scotoma

Ratra¹,

Gopalakrishnan

Dalan

et al. 2019

Clinical and Experimental Optometry

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Background: Patients with central scotoma have poor fixation stability and poor visual acuity. Acoustic biofeedback training can be an effective way to train such patients to eccentrically fixate. This study analyses the mean retinal sensitivity, saccadic velocity, and fixation stability after acoustic biofeedback training and shows correlation with age and scotoma size. Methods: Patients with irreversible central scotoma in both the eyes secondary to macular diseases were selected. After undergoing comprehensive low vision assessment, 19 patients who were willing were recruited for the acoustic biofeedback training to the better eye in 10 sessions, using the MP-1 Microperimeter. Mean retinal sensitivity, saccadic velocity, fixation stability before and after the acoustic biofeedback were recorded. Results: There were 17 men and two women. Ages ranged from 19-94 years (mean 54.63 AE 24.66). The scotoma size ranged from four to 20 degrees. Ten patients had agerelated macular degeneration, four had Stargardt disease, three had traumatic macular scar, two had scarred myopic choroidal neovascular membrane, and one had myopic macular degeneration. The vision improved from 1.06 AE 0.36 to 0.86 AE 0.33 logMAR (p < 0.0001). The mean retinal sensitivity improved from 2.1 AE 2.9 dB to 2.7 AE 3.1 dB (p = 0.01), with negative correlation with age (p = 0.01) and scotoma size (p = 0.02). Fixation stability improved with reduction in the bivariate contour ellipse area (p = 0.01). It showed negative correlation with age (p = 0.02) and scotoma size (p = 0.10). The saccadic velocity reduced from 0.34 /second to 0.26 /second but was not significant (p > 0.99). The majority (58 per cent) had their preferred retinal locus superior to the fovea. There was good agreement between bivariate contour ellipse area and MP-1 Microperimeter inbuilt fixation parameters. The effect was maintained at six months with slight reduction in fixation stability. Conclusion: Acoustic biofeedback can improve fixation behaviour, visual acuity and retinal sensitivity in patients with central scotoma. The results are better with younger age and smaller scotoma size.

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Section: Discussionmentioning

confidence: 83%

“…Patients with central scotoma have a strong tendency to develop a PRL in the left side of the visual field . However, the loci in other locations are also beneficial.…”

Section: Discussionmentioning

confidence: 99%

Visual rehabilitation using microperimetric acoustic biofeedback training in individuals with central scotoma

Ratra¹,

Gopalakrishnan

Dalan

et al. 2019

Clinical and Experimental Optometry

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“…These results seemed reasonable from a functional standpoint and agreed with previous studies. 20,[27][28][29][30][31] Field defects below fixation may interfere with many visual tasks that require information from the inferior visual field, such as walking, reading, and writing. The tendency for the visual system to locate visual field defects to the right of fixation was expected.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of Preferred Retinal Locus in Eyes with Central Vision Loss Secondary to Different Macular Lesions

Chen²,

Lin³

et al. 2021

Seminars in Ophthalmology

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Objective: Preferred retinal locus (PRL) training has been applied to low-vision rehabilitation for patients with central vision loss (CVL). This study aimed to explore the characteristics of a natural PRL in eyes with different macular lesions. The data may be useful in customizing training programs.Methods: A total of 72 eyes with CVL were included and assigned into two groups. In group A, 29 eyes diagnosed with macular holes featured relatively sharp borders and small areas of lesions. In group B, 44 eyes showed lesions characterized by irregular borders and large areas. The PRL location relative to a scotoma in the retina, fixation stability, and the average threshold surrounding the PRL were determined and compared between the two groups.Results: In group A, the PRL was located above in 48.28%, below in 27.59%, left in 62.07%, right in 31.03%, and inside in 3.45% of the eyes. In group B, the PRL was located above in 39.53%, below in 4.65%, left in 44.19%, right in 6.98%, and inside in 27.91% of eyes. The amount of retinal displacement occurring within 1° from an initial reference point (P< .05) and the 95% bivariate contour ellipse area (P< .05) in group A were respectively higher and lower than those in group B. However, the average thresholds around the PRLs in the two groups showed no significant difference (P > .05).Conclusions: A PRL to the left of or above a scotoma tends to develop to avoid the right and inferior field defect, regardless of the scale and boundary of lesions. Although light sensitivity around a PRL shows no relation to lesion features, fixation stability is worse in irregular and large lesions.

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“…In the inhibition group, the PRL was temporal or nasal to the scotoma (38%). Finally, Erbezci and Ozturk 50 reported that the most frequent location of the PRL in the retina was nasal, or in the left visual field.…”

Section: Binocular Fixational Control In Patients With Macular Diseasementioning

confidence: 98%

Binocular visual function and fixational control in patients with macular disease: A review

Micieli

Mandelcorn

Leibovitzh

et al. 2021

Ophthalmic Physiologic Optic

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Preferred Retinal Locus Locations in Age-Related Macular Degeneration

Abstract: The clinical PRL evaluation methodology that we describe can be used to facilitate making decisions on how to provide best visual rehabilitation to patients with a central scotoma.

Cited by 21 publications

References 20 publications

Visual rehabilitation using microperimetric acoustic biofeedback training in individuals with central scotoma

Visual rehabilitation using microperimetric acoustic biofeedback training in individuals with central scotoma

Characteristics of Preferred Retinal Locus in Eyes with Central Vision Loss Secondary to Different Macular Lesions

Binocular visual function and fixational control in patients with macular disease: A review

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