Pregnancy Specific β1 Glycoprotein: A Comparison of Analysis by Radioimmunoassay and Enzyme Linked ImmunoSorbent Assay.Observations on Patients with Malignant Teratoma of Testis

Abstract

Summary: A comparison of serum pregnancy specific ß 1 glycoprotein analysis by enzyme linked immunosorbent assay and radioimmunoassay has been made. Excellent correlation was obtained between the two methods but radioimmunoassay was found to be more precise and to have a lower detection limit than enzyme linked immunosorbent assay. Using the more sensitive radioimmunoassay system, 2 out of 10 control male sera were found to contain detectable levels of pregnancy specific ß l glycoprotein. Sequential results are presented on patients with diagnosed malignant teratoma of testis who were undergoing chemotherapy.