Preimplantation Hla Typing- Practical Tool for Stem Cell Transplantation Treatment of Congenital and Acquired Disorders

Abstract

It is well known that to achieve an acceptable engraftment and survival in stem cell therapy, an HLA identical stem cell transplant is strongly required. However, the availability of the HLA matched donors even among family members is extremely limited, so pre-implantation HLA typing provides an attractive practical tool of stem cell therapy for children requiring HLA matched stem cell transplantation.