Preinjury Warfarin Does Not Impact Outcome in Trauma Patients

Abstract

Our data suggest that the PIC of anticoagulation with warfarin does not adversely impact mortality or LOS outcomes in both head and non-head injured patients. In non-head injured patients, however, the occurrence rates and discharge destination were different. More research needs to be done to determine whether this is related to anticoagulation or other reasons (i.e., number of PICs). These data should be used when weighing risk/benefit ratios of prescribing chronic anticoagulation.

Clinically Suspected Coagulopathy in Blunt Head Trauma

“…Other investigators have found that head-injured patients on warfarin had a hospital length of stay and mortality rate that were not significantly different from those of matched controls (14).…”

Outcomes in Traumatic Brain Injury Patients on Preinjury Anticoagulation and Antiplatelet Agents

“…22,23 Wojcik et al also found no significant differences between warfarin and the control group with respect to mortality, ICU stay or LOS and discharge disposition. 24 …”

Gestion des accidents des anticoagulants chez le sujet âgé en médecine d’urgence

“…Le taux de mortalité d'une HIC après traumatisme crânien grave chez un patient sous AVK est de 25 à 50 %, risque vital trois à cinq fois supérieur à celui des HIC post-traumatiques en l'absence de traitement AVK [20][21][22]. Compte tenu de la fréquence des patients chuteurs dans la population gériatrique, il est important de noter que ni l'augmentation de fréquence de survenue d'une HIC sous AVK ni la surmortalité des patients sous AVK ne sont retrouvées quand ne sont pris en compte que les traumatismes crâniens mineurs, sans signe neurologique ni perte de connaissance [23][24][25].…”