Abstract:Primary and secondary anti-Thy-1 responses were elicited in C57BL/6Kh and (C57BL/ 6Kh × BALB/cKh)Fι mice by injection of either intact or sonicated Thy-1 disparate thymocytes as the source of the two forms of Thy-1 antigen – cell bound and cell free, respectively. The primary response was characterized by a high number of anti-Thy-1 plaque-forming cells in the spleen and a high titer of serum antibodies that belonged predominantly to the IgM class. The secondary response consisted of a moderate number of plaqu… Show more
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