Preliminary experience &amp; rationale of primary allo Simple Limbal Epithelial Transplantation (SLET) following surgical excision of Ocular Surface Tumors

Iyer, Geetha; Srinivasan, Bhaskar; Dhiman, Richa; Agarwal, Manokamna; Rajagopal, Rama

doi:10.1016/j.jtos.2021.07.007

Cited by 5 publications

(2 citation statements)

References 7 publications

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“…The review reported a favorable outcome of the procedure in subjects with a mean age of 21 years, but did not go into detail about whether or not to adopt peri-operative antibiotic prophylaxis [92]. The work of Iyer and colleagues reported the successful experimental therapy of an allo-Simple Limbal Epithelial Transplantation (allo-SLET) in 3 adult subjects after surgical removal of superficial squamous neoplasia, with postoperative use of 0.04% mitomycin C, 2 cycles, every other week [93]. Patil's group reported good success in the combination of amniotic membrane transplantation and 0.02% mitomycin applied to resected papillae in 4 pediatric patients (7-14 years old) treated for vernal keratoconjunctivitis, but did not mention pre-and intra-operative antibiotic therapy [94].…”

Section: Scenario #5 Pediatric Patient Undergoing Ocular Surface Tran...mentioning

confidence: 99%

Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study

et al. 2022

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Ocular surgery encompasses a wide range of procedures, including surgery of the tear ducts, eyelid, cornea and conjunctiva, lens, ocular muscle, and vitreoretinal and iris surgery. Operations are also performed for the removal of tumors, repairs of ocular trauma and, finally, corneal transplantation. Antibiotic prophylaxis for the prevention of surgical site infections (SSIs) in ocular surgery is a complex field in which shared lines of action are absent. In light of the scarcity of shared evidence in the use of ocular antimicrobial prophylaxis for the pediatric population, this consensus document aims to provide clinicians with a series of recommendations on antimicrobial prophylaxis for patients of neonatal and pediatric age undergoing eye surgery. The following scenarios are considered: (1) intraocular surgery; (2) extraocular surgery; (3) ocular trauma; (4) ocular neoplasm; (5) ocular surface transplantations; (6) corneal grafts. This work has been made possible by the multidisciplinary contribution of experts belonging to the most important Italian scientific societies and represents, in our opinion, the most complete and up-to-date collection of recommendations regarding clinical actions in the peri-operative environment in eye surgery. The application of uniform and shared protocols aims to improve surgical practice, through the standardization of procedures, with a consequent reduction of SSIs, also limiting the phenomenon of antimicrobial resistance.

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Section: Scenario #5 Pediatric Patient Undergoing Ocular Surface Tran...mentioning

confidence: 99%

Surgical Antimicrobial Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Eye Surgery: A RAND/UCLA Appropriateness Method Consensus Study

et al. 2022

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“…SLET is a novel surgery for transplantation of LESC and has been garnering popularity on account of its simple technique and effective outcomes. However, there is scarcity of literature on the outcomes of allo-SLET with a majority of existing reports pertaining to LSCD due to ocular burns [2] , [8] , [10] , [16] . Hence, in the current report we describe a case of VKC with bilateral LSCD which was managed with allo-SLET.…”

Section: Introductionmentioning

confidence: 99%