The Republic of the Union of Myanmar is one of many developing countries facing concerns about particulate matter (PM). Previously, a preliminary study of PM2.5 in 2018 suggested that the main source of PM in Yangon, the former capital, was vehicle emissions. However, this suggestion was not supported by any chemical composition data. In this study, to fill that gap, we quantitatively determined source contributions to coarse particulate matter (PM10) in Yangon, Myanmar. PM10 samples were collected in Yangon from May 2017 to April 2018 and chemically analyzed to determine composition. Chemical composition data for these samples were then used in the Chemical Mass Balance (CMB) model to identify the major sources of particulate matter in this area. The results indicate that PM10 composition varies seasonally according to both meteorological factors (e.g., precipitation and temperature) and human activities (e.g., firewood and yard waste burning). The major sources of PM in Yangon annually were dust, secondary inorganic aerosols (SIA), and secondary organic aerosols (SOA), while contributions from biomass burning were more important during the winter months.