Preliminary Report on Use of AlloDerm for Closure of Intraoral Defects After Buccal Mucosal Harvest

Kellner, Daniel; Fracchia, John A.; Voigt, Erich; Armenakas, Noel A.

doi:10.1016/j.urology.2006.12.008

Cited by 16 publications

(6 citation statements)

References 9 publications

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“…Nonetheless, possible donor‐site complications of BMG harvesting have been reported, including pain, swelling, salivatory changes, difficulty opening the mouth, damage to the parotid duct with symptoms of salivary obstruction, and injury to the long buccal and mental nerves, with subsequent paresthesia [7,8,22,23]. These complications usually occur after more extensive BMG harvesting, which is often necessary when treating patients with long urethral strictures [24]. In the report by Wood et al.…”

Section: Discussionmentioning

confidence: 99%

Urethral substitution using autologous lingual mucosal grafts: an experimental study

Song

et al. 2007

BJU International

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OBJECTIVE To investigate the feasibility of urethral substitution using free lingual mucosa grafts (LMGs) in a dog model. MATERIALS AND METHODS The study included 10 female mongrel dogs in which a 4 × 1 cm2 section of urethral mucosa was excised. The defect was immediately repaired with a size‐matched free LMG harvested from the inferior lateral surface of the tongue. A 12 F urethral catheter was kept inside the urethra for a mean of 7 days. At 3 months after the procedure, the patency of the urethra was assessed by both insertion of a 12 F catheter and by retrograde urethrography. Dogs were killed, the grafted areas excised, and evaluated by gross and histopathological examination. RESULTS All dogs survived the procedure and there were no tongue complications. One of the 10 dogs developed a slight urethral stricture near the proximal anastomosis. The remaining nine dogs voided spontaneously with no difficulty. Retrograde urethrography showed that no strictures or fistulas had formed. The LMGs shortened by 9.5% after surgery, from a mean (sd) of 4 (0.13) to 3.62 (0.11) cm (statistically significant, P < 0.05). Histological examination showed that the LMGs were well‐incorporated into the urethral walls and covered by a keratinized squamous epithelium. Neovascularization was evident beneath the grafts. CONCLUSION We successfully developed an dog model for free LMGs and showed the feasibility of this approach for urethral substitution.

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Section: Discussionmentioning

confidence: 99%

Urethral substitution using autologous lingual mucosal grafts: an experimental study

Song

et al. 2007

BJU International

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“…Our preference for this technique is predicated on data from our institution confirming that primary donor-site closure can be performed with minimal morbidity. 2,3 In addition, unnecessary costs associated with the use of allogenic tissue can be avoided. In our current study, the only long-term complication was perioral numbness, which occurred in one patient (1 percent) and resolved by the 1-year follow-up.…”

Section: Discussionmentioning

confidence: 99%

Single-Surgeon Experience of 87 Buccal Mucosal Graft Harvests

Cohen

Armenakas

Light

et al. 2012

Plastic &Amp; Reconstructive Surgery

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“…These complications usually occur after more extensive BMG harvesting, which is often necessary when treating patients with long urethral strictures [23,24].…”

Section: Discussionmentioning

confidence: 99%

Combined Buccal and Lingual Mucosa Grafts for Urethroplasty: An Experimental Study in Dogs

Song

et al. 2011

Journal of Surgical Research

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Preliminary Report on Use of AlloDerm for Closure of Intraoral Defects After Buccal Mucosal Harvest

Cited by 16 publications

References 9 publications

Urethral substitution using autologous lingual mucosal grafts: an experimental study

Urethral substitution using autologous lingual mucosal grafts: an experimental study

Single-Surgeon Experience of 87 Buccal Mucosal Graft Harvests

Combined Buccal and Lingual Mucosa Grafts for Urethroplasty: An Experimental Study in Dogs

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