Preliminary studies on the incorporation of sugars into naphthoquinones: synthesis of (1R,2S,3S,4R,4aS,11bS)-2-(benzyloxy)-1,2,3,4,4a,5-hexahydro-1,3,4-trihydroxy-11bH-benzo[b]carbazole-6,11-dione

Hydrogenation of (±)-trans-2-arylnitrocyclohexane derivatives over palladium

“…Earlier, Raney nickel [9][10][11][12], palladium [13,14] or platinum oxide [15,16] catalysts were applied in the hydrogenation of several nitrocyclohexanes. Thus, trans-8-nitro-9-(3,4-methylenedioxyphenyl)-1,4-dioxaspiro [4.5]decan-7-ol (1b) was reduced to the corresponding amine (2b) with 79% yield, over Raney nickel, in ethanol, at 30 bar and 50°C, after 17 h reaction time [11].…”

“…s, 2H, OCH 2 O), 6.68 (d, J = 8.0 Hz, 1H, ArH), 6.71 (s, 1H, ArH), 6.77 (d, J = 8.0 Hz, 1H, ArH); 13 C NMR (CDCl 3 , 125 MHz) d ppm 39.3, 41.9, 43.8, 57.5, 64.3, 65.1,70.1, 101.2, 108.1, 108.7, 108.9, 121.5, 135.9, 146.7, 148.3; GC-MS m/z (rel%) 293(1), 221(79), 163(12), 148(11), 135(100), 117(13), 87(16), 59(19), 43(17).…”