Preliminary study of a novel artificial anal sphincter with perception reconstruction

Ding, Han; Yan, Guozheng; Fang, Hua; Wang, Lichao

doi:10.1111/aor.14129

Cited by 6 publications

(4 citation statements)

References 24 publications

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“…88 Artificial Anal Sphincter Based on a Novel Clamping Mechanism (AASNCM) is composed of a control unit F I G U R E 3 Motor and spring-loaded AS devices. AS-SMA II (A) (reproduced with permission from Elsevier), 81 AS-SMA (B) (reproduced with permission from Wiley), 82 PAAS (C) 83 (reproduced with permission from Wiley), AASNCM (D) (reproduced with permission from Wiley), 84 SphinKeeper (E) (image from open access paper), 70 TMOD (F) (image from open access paper), 42 and ARTUS (G) (reproduced with permission from Wiley). 12 embedded in a clamping mechanism and a receiving coil.…”

Section: Fi Treatmentmentioning

confidence: 99%

Artificial sphincters: An overview from existing devices to novel technologies

et al. 2022

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Artificial sphincters (ASs) are used to replace the function of the biological sphincters in case of severe urinary and fecal incontinence (UI and FI), and gastroesophageal reflux disease (GERD). The design of ASs is established on different mechanisms, e.g., magnetic forces or hydraulic pressure, with the final goal to achieve a implantable and durable AS. In clinical practice, the implantation of in‐commerce AS is considered a reasonable solution, despite the sub‐optimal clinical outcomes. The failure of these surgeries is due to the malfunction of the devices (between 46 and 51%) or the side effects on the biological tissues (more than 38%), such as infection and atrophy. Concentrating on this latter characteristic, particular attention has been given to the interaction between the biological tissues and AS, pointing out the closing mechanism around the duct and the effect on the tissues. To analyze this aspect, an overview of existing commercial/ready‐on‐market ASs for GERD, UI, and FI, together with the clinical outcomes available from the in‐commerce AS, is given. Moreover, this invited review discusses ongoing developments and future research pathways for creating novel ASs. The application of engineering principles and design concepts to medicine enhances the quality of healthcare and improves patient outcomes. In this context, computational methods represent an innovative solution in the design of ASs, proving data on the occlusive force and pressure necessary to guarantee occlusion and avoid tissue damage, considering the coupling between different device sizes and individual variability.

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Section: Fi Treatmentmentioning

confidence: 99%

Artificial sphincters: An overview from existing devices to novel technologies

et al. 2022

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“…As shown in Figure 2B,C, this study employs a strain gauge sensor design consisting of a steel sheet substrate, a Piezoresistive Membrane, and a silicon adhesive. The strain gauge sensor has been validated for good sensing performance 17 …”

Section: Methodsmentioning

confidence: 99%

Simulation of artificial anal sphincter motion and interaction with intestinal environment using SOFA

Liu,

Wang,

Yan

et al. 2023

Artificial Organs

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BackgroundArtificial anal sphincter is an implantable medical device for treating fecal incontinence. Reasonable simulation facilitates the advancement of research and reduces experiments on biological tissue. However, the device's clamping motion and sensor interaction with the intestine in the simulation still require further exploration. This article presents a simulation of the artificial anal sphincter's clamping and sensing and its interaction with the intestinal environment using the Simulation Open Framework Architecture (SOFA).MethodsFirstly, the proposed simulation algorithm and its principles in SOFA are analyzed. Secondly, the clamping motion and sensor system of the artificial anal sphincter are simulated. Thirdly, a finite element model of intestine is established based on the properties of intestinal soft tissue. Finally, the in vitro experiments are performed.ResultsThe simulation results indicate that the sensor system of the artificial anal sphincter has good sensing performance during the clamping motion and fecal accumulation process. Experiments have shown that optimal sensory capabilities can be achieved as the posture of the artificial anal sphincter with a roll angle between 20° and 40°. The comparison demonstrates a mean absolute error of 10%–20% between simulation and in vitro experimental results for sensor forces, which verifies the effectiveness of the simulation.ConclusionThe proposed novel simulation achieves a more comprehensive interaction between the artificial anal sphincter motion and intestinal environment. This study may provide more effective simulation data for guidance in improving the performance of sensor perception of artificial anal sphincter for further research.

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“…Then, the effects of nonlinear errors can be eliminated. The strain gauge sensor has been validated for good sensing performance [ 28 ].…”

Section: Overview Of Strain Gauge Sensors and Aas System With Percept...mentioning

confidence: 99%

A Novel Sensor System for In Vivo Perception Reconstruction Based on Long Short-Term Memory Networks

Ding

Yan

Wang

et al. 2022

Sensors

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Monitoring bodily pressure could provide valuable medical information for both doctors and patients. Long-term implantation of in vivo sensors is highly desirable in situations where perception reconstruction is needed. In particular, for fecal incontinence, artificial anal sphincters without perceptions could not remind patients when to defecate and even cause ischemic tissue necrosis due to uncontrolled clamping pressure. To address these issues, a novel self-packaging strain gauge sensor system is designed for in vivo perception reconstruction. In addition, long short-term memory (LSTM) networks, which show excellent performance in processing time series-related features and fitting properties, are used in this article to improve the prediction accuracy of the perception model. The proposed system has been tested and compared with the traditional linear regression (LR) approach using data from in vitro experiments. The results show that the Root-Mean-Square Error (RMSE) is reduced by more than 69%, which demonstrates that the prediction accuracy of the proposed LSTM model is higher than that of the LR model to reach a more accurate prediction of the amount of intestinal content. Furthermore, outcomes of in vivo experiments show that the robustness of the novel sensor system based on long short-term memory networks is verified through experiments with limited data.

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Preliminary study of a novel artificial anal sphincter with perception reconstruction

Cited by 6 publications

References 24 publications

Artificial sphincters: An overview from existing devices to novel technologies

Artificial sphincters: An overview from existing devices to novel technologies

Simulation of artificial anal sphincter motion and interaction with intestinal environment using SOFA

A Novel Sensor System for In Vivo Perception Reconstruction Based on Long Short-Term Memory Networks

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