Premature ejaculation: Pharmacotherapy vs group psychotherapy alone or in combination

Pavone, Carlo; Abbadessa, Daniela; Gambino, Giuseppa; Scaduto, Giovanna; Vella, Marco

doi:10.4081/aiua.2017.2.114

Cited by 8 publications

(10 citation statements)

References 18 publications

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“…After removing 1736 papers through the title/abstract screening, 91 were retrieved as full text. Of the 91 full text, 36 studies were excluded because they were theoretical, opinion, focused on erectile dysfunction or included only pharmacological treatments, leaving 54 studies to be included in the systematic review 14–67 …”

Section: Resultsmentioning

confidence: 99%

Non‐pharmacological approaches for treatment of premature ejaculation: a systematic review

Pizzol¹,

Sánchez

Ilie

et al. 2023

Trends Urol & Men's Health

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Premature ejaculation is a common male condition worldwide with prevalence estimates varying from 30% to 85%. Owing to the lack of a clear definition and a clear understanding of the potentially multifactorial pathophysiology, treatment remains challenging. The aim of this systematic review was to evaluate the non‐pharmacological treatment modalities for PE to inform clinical practice and patients.

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Section: Resultsmentioning

confidence: 99%

Non‐pharmacological approaches for treatment of premature ejaculation: a systematic review

Pizzol¹,

Sánchez

Ilie

et al. 2023

Trends Urol & Men's Health

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“…Considering all these negative effects, behavioral treatments and pelvic floor training to alleviate premature ejaculation are of great importance. Although there are many studies [ 16 , 19 , 23 ] examining the effects of behavioral therapy and pelvic floor exercises on men with premature ejaculation in the literature, no study has been found comparing the stop-start technique with the stop-start technique together with sphincter control training. This study is expected to contribute to the literature by investigating the stop-start technique, which is a current approach in the treatment of premature ejaculation, and comparing its results with the stop-start technique together with sphincter control training.…”

Section: Discussionmentioning

confidence: 99%

“…When we look at the studies in the literature, we see the studies on the effect of the stop-start technique on the PEDT value. For example, in the study of Pavone et al (2017), it was observed that the PEDT value decreased after the application [ 16 ]. In Mantovani’s (2017) study on 18 patients, it was found that the PEDT value decreased in the post-test compared to the pre-test [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

“…This technique is repeated several times until ejaculation [ 13 , 14 ]. When the literature is examined, many studies have revealed the positive effect of the stop-start technique on premature ejaculation [ 15 , 16 ]. For example, in the study of Makwana and Patil (2012), it was stated that the stop-start technique applied to 30 men increased the time spent in the vagina [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of the results of stop-start technique with stop-start technique and sphincter control training applied in premature ejaculation treatment

Doğan

Keçe

2023

PLoS ONE

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Background The aim of this study is to compare the results of stop-start technique with stop-start technique together with sphincter control training applied in the treatment of premature ejaculation. Methods This research was conducted as a pre-test post-test quasi-experimental study. The sample of the study consisted of 80 men. The study was conducted on men who applied to the urology outpatient clinic of LIV Hospital, a prıvate hospital, in Gaziantep, Turkey, between 01 October 2021 and 01 March 2022. “Personal Information Form”, “Intravaginal Ejaculation Latency Time (IELT)”, “Fold Increase Intravaginal Ejaculation Latency Time (F-IELT)” “Premature Ejaculation Diagnostic Tool (PEDT) Questionnaire” and “Arabic Index Premature Ejaculation (AIPE)” were used as the data collection tools. Behavioral therapy, consisting of a total of 6 sessions, was applied once every two weeks, with each session lasting for 45 minutes. After 3rd and 6th months from the beginning of the application, the data collection tools were applied again. “Stop-Start Technique (Group A)” and “Stop-Start Technique and Sphincter Control Training (Group B)” were used in the treatment. Results In both groups, the IELT and AIPE values after 3rd and 6th months from the beginning of the application were statistically higher than those obtained before (p<0.05). IELT and AIPE values increased more in Group B than Group A (p<0.05). F-IELT values after 6th months from the beginning of the application were found to be statistically significant with a low level of effect size than those obtained before (p<0.05, Cohen’s d = 0.027). In both groups, the PEDT values in the 3rd and 6th months after the application were statistically lower than those seen before (p<0.05). PEDT value decreased more in Group B than Group A (p<0.05). The differences between the two groups’ IELT (Cohen’s d = 0.011), AIPE (Cohen’s d = 0.044), and PEDT (Cohen’s d = 0.066) values in the 3rd month after the application and IELT (Cohen’s d = 0.025), AIPE (Cohen’s d = 0.048), and PEDT (Cohen’s d = 0.024) values in the 6th month after the application were found to be clinically weak. Conclusions It was determined that the stop-start technique given to men with premature ejaculation increased the time spent in the vagina and eliminated the problem of premature ejaculation. It was determined that the stop-start technique in combination with sphincter control training were more effective than the stop-start technique alone.

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“…Sexual male dysfunction is an extremely common condition that manifests itself with erectile disorder (ED) and premature ejaculation (EP) (1), often present at the same time. In everyday clinical practice, both pathologies require a multidisciplinary approach in the diagnostic phase and in the therapeutic management (2,3) due to their multifactorial genesis, such as psychological factors and endothelial dysfunction. Female sexual dysfunctions are understudied, despite the incidence being alarmingly high: in a 30 years ago study, 76% of women were living with some symptoms of sexual dysfunction (4), while more recent literature suggest that prevalence is around 43% (5).…”

Section: Introductionmentioning

confidence: 99%

Sexual dysfunction in dialytic patients. A prospective cross-sectional observational study in two hemodialysis centers

Pavone

Fede

Mannone

et al. 2021

Arch Ital Urol Androl

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Objectives: Incidence and prevalence of patients in dialytic therapy increased considerably in recent years. The onset of new issues, once overshadowed, linked to a lower quality of life like sexual dysfunction became increasingly common. The first study in this area, dating back to the 1970s, shows the high prevalence of sexual dysfunction among patients in dialytic therapy of both sexes. Later studies proved an association of sexual dysfunction with psyche disorders, anxiety, depression and lack of self-confidence. The aim of this study is to describe the incidence of male and female sexual main dysfunctions, the latter not least in literature, in patients in hemodialytic therapy. With this aim two dialytic centers have been compared, one located in northern Italy and one in southern Italy, and the different prevalence has been compared to the general population. Methods: We conducted a prospective cross-sectional observational study in patients undergoing dialytic therapy in two hemodialysis centers, one located in Palermo and one in Lecco. Male sexual dysfunction was investigated by the International Index of Erectile Function-15 (IIEF15) questionnaire and the Premature Ejaculation Diagnotic Tool (PEDT) questionnaire, and the female dysfunction by Female Sexual Function Index (FSFI) questionnaire. Criteria for inclusion in our study were: age < 75 years and dialytic age > 3 months; exclusion criteria were: advanced cancer diseases, life expectancy < 6 months, previous urological manipulation, anti-androgenic therapy, sexual dysfunction unrelated to kidney disease, psychiatric disorders. Data were compared with mean-standard deviation (SD) and with the variance analysis (ANOVA). A value of p < 0.05 is considered significant. Discrete data were analyzed with contingency analysis. A chi2 < 0.05 was considered significant. Results: Data of 78 patients have been collected. Mean age and dialytic time were 54 ± 12 years and 42 ± 35 month; 33 patients were from Palermo and 24 from Lecco; 21 patients were excluded. Age and dialytic age of the two subgroups did not demonstrate statistically significant differences. Between the two centers there was a statistically significant difference (p < 0.005) in the distribution of basic nephropathy: an higher incidence of diabetic and obstructive nephropathy has been observed in the southern center compared to northern center, while glomerulonephritis and polycystic kidney disease had an higher incidence in the northern center compared to southern one. The main sexual dysfunctions in both sexes, erectile dysfunction (ED) and premature ejaculation (PE) in men and orgasm disorder and pelvic pain in women, have been investigated. ED was present in 70% of hemodialyzed patients, which is an higher incidence compared to the general population. The severity of ED between patients of the two groups was significantly different (chi2 < 0.001) with higher incidence of moderate/severe forms in northern Italy. The score, in addition to discrete data (severe, moderate, mild, absence), of ED was significantly different (p < 0.001) between patients of the two centers (22 ± 7 Palermo vs. 9 ± 8, Lecco). The PE was absent in 20 patients (54%), present in 12 patients (32%) and probable in 5 patients (14%) (scores of 7.6 ± 4.0 and 8.9 ± 6.8, respectively in Palermo and Lecco patients). For women, orgasmic dysfunction was severe in 10 patients (50%), mild in 4 patients (20%), very mild in 5 patients (25%), while it was normal in 1 patient (5%), with a statistically significant difference (p< 0.05) between Palermo and Lecco patients (3.0 ± 1.4 vs 1.2 ± 2.0). Sexual pain in women was severe in 11 patients (55%), moderate in 4 patients (20%) and mild in 5 patients (25%). Sexual pain was present in all patients (p < 0.05).Conclusions: Regardless of sex, sexual dysfunction is one of the most common side effect in patients with end stage renal disease in dialytic therapy. Our study confirms literature data. The growing number of the dialytic population with sexual disorders needs specialist support to improve quality of life of these patients.

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Premature ejaculation: Pharmacotherapy vs group psychotherapy alone or in combination

Cited by 8 publications

References 18 publications

Non‐pharmacological approaches for treatment of premature ejaculation: a systematic review

Non‐pharmacological approaches for treatment of premature ejaculation: a systematic review

Comparison of the results of stop-start technique with stop-start technique and sphincter control training applied in premature ejaculation treatment

Sexual dysfunction in dialytic patients. A prospective cross-sectional observational study in two hemodialysis centers

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