Prenatal Detection of Two Different Monosomic Cell Lines by Chorionic Villus Sampling

Hsu, Te‐Yao; Liou, Jui-Der; Copel, Joshua A.; Mahoney, Maurice J.; Breg, W. Roy; Yang‐Feng, Teresa L.

doi:10.1002/(sici)1097-0223(199602)16:2<169::aid-pd819>3.0.co;2-t

Cited by 3 publications

(1 citation statement)

References 14 publications

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“…It was only found in embryonic pregnancies, in agreement with previous results [4,5,12]. Monosomy and even mosaicism were found to induce early miscarriages [13]. Trisomy was the most common subtype, with trisomy 16 being the most frequent trisomy in both embryonic and anembryonic miscarriages, in agreement with previous findings [4,5].…”

Section: Discussionsupporting

confidence: 92%

Chromosome distribution of early miscarriages with present or absent embryos: female predominance

Cheng

Tsai

et al. 2014

J Assist Reprod Genet

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Purpose The objective of this study is to compare the chromosomal distribution of early miscarriages with or without embryonic poles. Materials and methods It was a retrospective study of 223 women who underwent dilation and curettage (D&C) between 1995 and 2013 for early miscarriages. The presence or absence of a fetal pole was evaluated by abdominal or transvaginal ultrasound. Cytogenetic tests of products of conception following culture were determined in both groups. Results Of the 223 early miscarriages, 143 had embryos and 80 did not. The abnormality rate differed significantly (61.5 % vs. 46.3 %, p<0.05), with trisomy 18, 21 and 45X found only in miscarriages with embryos. There were no significant differences between groups in rates of triploidy, tetraploidy, mosaicism, structure and double abnormality. The female abortus rate was higher in miscarriages with or without embryonic poles, as well as in groups with normal and abnormal karyotypes.Conclusions Chromosome distribution differs in miscarriages with or without embryonic poles. The ultrasound findings might offer different direction to determine the causes of early miscarriages. The higher female abortus rate may be associated with early selection.

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Section: Discussionsupporting

confidence: 92%

Chromosome distribution of early miscarriages with present or absent embryos: female predominance

Cheng

Tsai

et al. 2014

J Assist Reprod Genet

Self Cite

View full text Add to dashboard Cite

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Prenatal Diagnosis of Chromosomal Abnormalities through Chorionic Villus Sampling and Amniocentesis

Benn

2015

Genetic Disorders and the Fetus

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Prenatal Diagnosis of Chromosomal Abnormalities through Chorionic Villus Sampling and Amniocentesis

Benn¹

2021

Genetic Disorders and the Fetus

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Prenatal Detection of Two Different Monosomic Cell Lines by Chorionic Villus Sampling

Cited by 3 publications

References 14 publications

Chromosome distribution of early miscarriages with present or absent embryos: female predominance

Chromosome distribution of early miscarriages with present or absent embryos: female predominance

Prenatal Diagnosis of Chromosomal Abnormalities through Chorionic Villus Sampling and Amniocentesis

Prenatal Diagnosis of Chromosomal Abnormalities through Chorionic Villus Sampling and Amniocentesis

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