Prenatal MRI of neck masses with special focus on the evaluation of foetal airway

Ravelli, Anna; Napolitano, Marcello; Rustico, Mariangela; Riccipetitoni, Giovanna; Leo, Giovanni Di; Righini, Andrea; Sardanelli, Francesco

doi:10.1007/s11547-019-01049-1

Cited by 5 publications

(9 citation statements)

References 26 publications

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“…However this only amounted to 54 studies in total as some artices described different tests from the same study. Of the 134 indirect evidence papers or abstracts, 133 were synthesised41–174 as well as a single trial record 175. None of the seven included trials identified from trial registries reported interim or final results and only four remain active 176–179.…”

Section: Resultsmentioning

confidence: 99%

“…For both risk of bias and applicability to the review question, the majority (n=129) had some concerns,41 42 44–67 69–87 89–149 151–170 172–174 and five had a high level of concern43 68 88 150 171 (figure 3).…”

Section: Resultsmentioning

confidence: 99%

“…44 163 170 In a stillbirth population, there was a mixture of results, with seven studies favouring the index test, 69 75 77 133 159 160 166 three studies favouring the reference standard 65 85 167 and one having a split opinion. 52 Contrastingly, four studies assessing a neonatal population favoured autopsy, 52 65 143 147 with a fifth study being indiscriminate between the tests 130 (online supplemental figure 1G).…”

Section: Indirect Evidencementioning

confidence: 97%

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Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy

et al. 2023

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ObjectivesTo assess the diagnostic accuracy of non-invasive or minimally invasive autopsy techniques in deaths under 1 year of age.DesignThis is a systematic review of diagnostic test accuracy. The protocol is registered on PROSPERO.ParticipantsDeaths from conception to one adjusted year of age.Search methodsMEDLINE (Ovid), EMBASE (Ovid), CINAHL (EBSCO), the Cochrane Library, Scopus and grey literature sources were searched from inception to November 2021.Diagnostic testsNon-invasive or minimally invasive diagnostic tests as an alternative to traditional autopsy.Data collection and analysisStudies were included if participants were under one adjusted year of age, with index tests conducted prior to the reference standard.Data were extracted from eligible studies using piloted forms. Risk of bias was assessed using Quality Assessment of Diagnostic Accuracy Studies-2. A narrative synthesis was conducted following the Synthesis without Meta-Analysis guidelines. Vote counting was used to assess the direction of effect.Main outcome measuresDirection of effect was expressed as percentage of patients per study.FindingsWe included 54 direct evidence studies (68 articles/trials), encompassing 3268 cases and eight index tests. The direction of effect was positive for postmortem ultrasound and antenatal echography, although with varying levels of success. Conversely, the direction of effect was against virtual autopsy. For the remaining tests, the direction of effect was inconclusive.A further 134 indirect evidence studies (135 articles/trials) were included, encompassing 6242 perinatal cases. The addition of these results had minimal impact on the direct findings yet did reveal other techniques, which may be favourable alternatives to autopsy.Seven trial registrations were included but yielded no results.ConclusionsCurrent evidence is insufficient to make firm conclusions about the generalised use of non-invasive or minimally invasive autopsy techniques in relation to all perinatal population groups.PROSPERO registration numberCRD42021223254.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Indirect Evidencementioning

confidence: 97%

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Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy

et al. 2023

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“…Although this is unlikely to present as an acute emergency, careful planning and identification of the relationship between the tumour and adjacent airway and vascular anatomy is crucial. Antenatal MRI has recently been hailed as the most definitive imaging tool for these cases [43], allowing for surgical planning of an ‘ex-utero intrapartum treatment’ (‘EXIT’) of the baby, followed by definitive surgery to remove the tumour. Given the location and potential airway complications in such cases, successful long-term outcomes are usually achieved in just over half of cases [44].…”

Section: Intra-thoracic Emergenciesmentioning

confidence: 99%

Emergency imaging in paediatric oncology: a pictorial review

et al. 2019

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Despite the decline in mortality rates over the last 20 years, cancer remains one of the leading causes of death in children worldwide. Early recognition and treatment for acute oncological emergencies are vital in preventing mortality and poor outcomes, such as irreversible end-organ damage and a compromised quality of life. Imaging plays a pivotal and adjunctive role to clinical examination, and a high level of interpretative acumen by the radiologist can make the difference between life and death. In contrast to adults, the most accessible crosssectional imaging tool in children typically involves ultrasound. The excellent soft tissue differentiation allows for careful delineation of malignant masses and along with colour Doppler imaging, thromboses and large haematomas can be easily identified. Neurological imaging, particularly in older children is an exception. Here, computed tomography (CT) is required for acute intracranial pathologies, with magnetic resonance imaging (MRI) providing more definitive results later. This review is divided into a 'body systems' format covering a range of pathologies including neurological complications (brainstem herniation, hydrocephalus, spinal cord compression), thoracic complications (airway obstruction, superior vena cava syndrome, cardiac tamponade), intra-abdominal complications (bowel obstruction and perforation, hydronephrosis, abdominal compartment syndrome) and haematological-related emergencies (thrombosis, infection, massive haemorrhage). Within each subsection, we highlight pertinent clinical and imaging considerations. The overall objective of this pictorial review is to illustrate how primary childhood malignancies may present with lifethreatening complications, and emphasise the need for imminent patient management.

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“…US is often considered the first line screening imaging modality and, depending on its findings, may determine the necessity for the next best diagnostic step, including computed tomography (CT), magnetic resonance imaging (MRI) and other techniques (8)(9)(10)(11)(12)(13)(14)(15). The utility of US for interventional procedure guidance such as for tissue sampling and biopsy, interventional drainage procedure or surgical excision is well recognized (16)(17)(18)(19)(20).…”

Section: Introductionmentioning

confidence: 99%

Narrative review of multiparametric ultrasound in parotid gland evaluation

Martino¹,

Fodor²,

Fresilli³

et al. 2020

Gland Surg

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Disorders affecting parotid gland represent a heterogeneous group comprising congenital, inflammatory and neoplastic diseases which show a focal or diffuse pattern of appearance. The differentiation of neoplastic from non-neoplastic conditions of parotid glands is pivotal for the diagnostic imaging. Frequently there is evidence of overlapping between the clinical and the imaging appearance of the various pathologies. The parotid gland is also often object of study with the combination of different techniques [ultrasound-computed tomography-magnetic resonance imaging (US-CT-MRI), ex.]. Compared to other dominant methods of medical imaging, US has several advantages providing images in real-time at lower cost, and without harmful use of ionizing radiation and of contrast enhancement. B-mode US, and the microvascular pattern color Doppler are usually used as first step evaluation of parotid lesions. Elastography and contrast-enhanced US (CEUS) has opened further possible perspectives to improve the differentiationbetween benign and malignant parotid lesions. The characterization of the parotid tumors plays a crucial role for their treatment planning and for the prediction of possible surgical complications. We present, here an updated review of the most recurrent pathologies of parotid gland focusing on the diagnostic power of multiparametric US including CEUS and ultrasound elastography (USE); limitations, advantages and the main key-points will be presented

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Prenatal MRI of neck masses with special focus on the evaluation of foetal airway

Cited by 5 publications

References 26 publications

Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy

Are non-invasive or minimally invasive autopsy techniques for detecting cause of death in prenates, neonates and infants accurate? A systematic review of diagnostic test accuracy

Emergency imaging in paediatric oncology: a pictorial review

Narrative review of multiparametric ultrasound in parotid gland evaluation

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