Preoperative Biometric Parameters Predict the Vault after ICL Implantation: A Retrospective Clinical Study

Zheng, Qianyin; Xu, Wen; Liang, Guihong; Wu, Jing; Shi, Junting

doi:10.1159/000446185

Cited by 24 publications

(25 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our multiple regression analysis yielded a result close to the highest linear fitting value reported in previous vault prediction studies (adjusted R 2 = 0.411) [6][7][8][9][10]. However, linear regression analysis explained no more than half of the vault prediction.…”

Section: Discussionsupporting

confidence: 84%

“…ICL implantation remains challenging because of difficulties in determining the appropriate lens size and predicting the vault value. Recent studies utilizing regression analyses have reported that the postoperative vault can only be explained in approximately 41.0% of cases [6][7][8][9][10]. In the present study, we performed linear regression and neural network analyses to examine the relationship between the preoperative biometric variables and the postoperative vault.…”

Section: Discussionmentioning

confidence: 95%

“…Previous studies have indicated that the ICL vault can be roughly modeled using linear regression (R 2 ≤ 0.41 in multiple regression analysis) of various combinations of preoperative biometrics [6][7][8][9][10]. However, to the best of our knowledge, there is no standard formula for predicting the vault, and no studies to date have thoroughly investigated the performance of all individual preoperative biometric factors and their combinations in predicting the ICL vault.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Use of neural networks to predict vault values after implantable collamer lens surgery

Liu

Lei

et al. 2021

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

Background Appropriate sizing of the implantable collamer lens (ICL) and accurate prediction of the vault are crucial prior to surgery. However, sometimes, the vault value is higher or lower than predicted, necessitating reoperation. The present study aimed to develop neural networks for improving predictions of vault values following ICL implantation based on preoperative biometric data. Methods This retrospective study included 137 eyes of 74 patients with ICLs. Linear regression and neural network analyses were used to examine the relationship between vault values at the 6-month follow-up and preoperative parameters (e.g., ICL characteristics and biometrics). Results Linear regression analysis revealed that vault values were correlated with five variables: ICL size, anterior chamber depth (ACD), angle-to-angle (ATA), white-to-white (WTW), and lens thickness (LT) (adjusted R2 = 0.411). Inclusion of more input variables was associated with better performance in the neural network analysis. The degree of fit when all 11 variables were included in the neural network model was close to 1 (R2 = 0.98). R2 values for the quaternary neural network model enrolling four input variables (ICL size, ATA, ACD, and LT) reached 0.90. Conclusions A neural network equation including the ICL size and biometric parameters of the anterior segment (ATA, ACD, and LT) can be used to predict the postoperative vault, aiding in the selection of an appropriate ICL size and reducing the need for reoperation after surgery.

show abstract

Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 95%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Use of neural networks to predict vault values after implantable collamer lens surgery

Liu

Lei

et al. 2021

Graefes Arch Clin Exp Ophthalmol

View full text Add to dashboard Cite

show abstract

“…The need for predicting the vault has led to the development of predictive models using biometric and lens features. 7 – 11 Despite the variety of associations put forward, the ability of explaining the vault preoperatively is limited to approximately 40% 9 , 10 and decreases to 14% if the prediction is restricted to an optimal vault range. 12 Several arguments have been presented to justify the limited predictability of the models.…”

Section: Introductionmentioning

confidence: 99%

<p>Inter-Eye Vault Differences of Implantable Collamer Lens Measured Using Anterior Segment Optical Coherence Tomography</p>

Manito¹,

Trancón²,

Sierra³

et al. 2020

OPTH

View full text Add to dashboard Cite

Purpose The distance between an implantable collamer lens (ICL) and the crystalline lens, namely vault, is a space regulated by the interaction of the ICL and the anatomical structures of the eye. This study analysed the differences in vault size between fellow eyes with similar anterior segment biometry. Patients and Methods A retrospective case series analysed 109 cases of patients bilaterally implanted with EVO-V4c. Patients were analysed pre- and postoperatively using anterior segment optical coherence tomography. The range of vault inter-eye differences was defined as the 95% confidence interval of the differences. Bivariate correlation was applied to seek for associations between vault inter-eye differences with biometric and lens parameters (angle-to-angle, anterior chamber depth, crystalline lens rise, central corneal thickness, central keratometry, ICL spherical equivalent, horizontal compression, postoperative pupil diameter and vault). Results Mean vault inter-eye differences were similar between fellow eyes (26.0 ± 122.5 µm). The 95% confidence interval range of the differences was ±240.1 µm, nearly 50% of the cases presented vault inter-eye differences higher than 100 µm. The vault of the first operated eye explained 81% of the variance in the second eye vault. Vault inter-eye differences were positively correlated with the level of horizontal compression and with vault magnitude. Conclusion Vaults measured in fellow eyes may present considerable differences, which can reach 25% of the common vault range. This reflects some degree of baseline variability in the vault. Clinically, these differences assume special relevance in cases where low or high vaults are expected.

show abstract

“…Therefore, we speculated that pupil constriction due to the disappearance of the effect of the mydriatic agent played a very important role in vault reduction within 1 day after surgery. Finally, several studies have proven that the morphology of the crystalline lens also has an in uence on vault after ICL implantation [32][33][34]. ICL vault was affected by changes in crystalline lens rise (CLR) caused by accommodation or light condition changes [20,35,36].…”

Section: Discussionmentioning

confidence: 99%

Short-term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation

Zhu¹,

Chen²,

Zhu³

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: To describe the very early changes in vault in the first month after Implantable Collamer Lens (ICL) implantation and to evaluate the effect of preoperative biometric factors on vault.Methods: A total of 83 eyes from 83 subjects with complete data who met follow-up requirements were recruited in this retrospective study between May 2019 and March 2020. We quantitatively assessed postoperative vault at 2 hours, 1 day, 1 week, and 1 month following implantation. Associations between postoperative vault and age, ICL size, spherical equivalent (SE), axial length (AL), central corneal thickness (CCT), flat K, steep K, mean K, anterior chamber depth (ACD), crystalline lens thickness (LT), white-to-white (WTW) diameter obtained by three devices, horizontal and vertical sulcus-to-sulcus (STS) diameter, bright and dark pupil sizes (BPS and DPS) and DPS-BPS were investigated using Spearman’s correlation analysis and stepwise multiple regression analysis.Results: The mean vault values at 2 hours, 1 day, 1 week, and 1 month after ICL implantation were 672.05 ± 30.72, 389.15 ± 28.33, 517.23 ± 30.76 and 530.12 ± 30.22 μm, respectively. There were significant differences in vault values between 2 hours, 1 day and 1 week after the operation. ICL size (β = 0.942; p < 0.001), followed by horizontal STS (β = -0.517; p < 0.001), crystalline LT (β = -0.376; p < 0.001) and vertical STS (β = -0.257; p = 0.017), significantly influenced vault at 1 month after the operation. The multiple regression equation was expressed as follows: central vault (μm) = -1369.05+ 657.121 × ICL size- 287.408 × horizontal STS - 432.497 × crystalline LT - 137.33 × vertical STS (adjusted R2 = 0.643).Conclusions: After ICL implantation, vault decreased and then increased, but it did not return to the vault value at 2 hours after surgery. ICL size, horizontal and vertical STS and crystalline LT were key factors for predicting postoperative vaulting.

show abstract

Preoperative Biometric Parameters Predict the Vault after ICL Implantation: A Retrospective Clinical Study

Cited by 24 publications

References 20 publications

Use of neural networks to predict vault values after implantable collamer lens surgery

Use of neural networks to predict vault values after implantable collamer lens surgery

<p>Inter-Eye Vault Differences of Implantable Collamer Lens Measured Using Anterior Segment Optical Coherence Tomography</p>

Short-term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation

Contact Info

Product

Resources

About

Preoperative Biometric Parameters Predict the Vault after ICL Implantation: A Retrospective Clinical Study

Cited by 24 publications

References 20 publications

Use of neural networks to predict vault values after implantable collamer lens surgery

Use of neural networks to predict vault values after implantable collamer lens surgery

<p>Inter-Eye Vault Differences of Implantable Collamer Lens Measured Using Anterior Segment Optical Coherence Tomography</p>

​Short-term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation

Contact Info

Product

Resources

About

Short-term changes in and preoperative factors affecting vaulting after posterior chamber phakic Implantable Collamer Lens implantation