“…General are: immunological diseases (autoimmune, collagen vascular, immune deficiency); pregnancy or breast feeding; the tendency to form keloids; diabetes; and systemic administration of isotretionin or amiodarone. Ophthalmic are: dry eye; neurotrophic keratitis; herpes zoster ophthalmicus / keratitis herpetica; glaucoma; ectatic corneal dystrophy (keratoconus, keratoglobus); highly irregular astigmatism; uveitis, diabetic retinopathy; progressive retinal disease and previously performed radial keratotomy (8).…”