Preoperative Osteopenia as Risk Factor for Death from Other Diseases After Gastrectomy in Elderly Patients

SHIMIZU, SHOTA; MATSUNAGA, TOMOYUKI; SAKANO, YU; MAKINOYA, MASAHIRO; SHISHIDO, YUJI; MIYATANI, KOZO; KONO, YUSUKE; MURAKAMI, YUKI; HANAKI, TAKEHIKO; KIHARA, KYOICHI; YAMAMOTO, MANABU; TOKUYASU, NARUO; TAKANO, SHUICHI; SAKAMOTO, TERUHISA; HASEGAWA, TOSHIMICHI; FUJIWARA, YOSHIYUKI

doi:10.21873/invivo.13375

Cited by 1 publication

(1 citation statement)

References 31 publications

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“…The independent association of PNI with OS was found to be significant in 23 studies, while 13 did not found a significant relationship in multivariate analysis. Thirteen studies supported the prognostic value of PNI in gastric cancer patients [25,28,29,[37][38][39]41,45,48,50,54,56,58], one in colorectal cancer [60], one in oesophageal squamouscell carcinoma (ESCC) [53], three in lung cancer [17,35,49], one in diffuse large B cell lymphoma [52], one in hepatocellular carcinoma [26], one in osteosarcoma [31], one in digestive cancer [17], and one in cancer patients in general [17]. The relationship between PNI and CSS was assessed by five studies, and none supported the relationship.…”

Section: Prognostic Nutritional Indexmentioning

confidence: 96%

The Prognostic Role of Prognostic Nutritional Index and Controlling Nutritional Status in Predicting Survival in Older Adults with Oncological Disease: A Systematic Review

Ferreira,

Fernandes,

Carvalho

et al. 2024

Onco

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The increase in new cancer diagnoses in the elderly calls for new, accessible, and easy-to-use prognostic tools that contribute to lowering the burden of the disease. Recognising the importance of inflammation and nutritional status in the progression of the disease, the purpose of this systematic review was to synthesise the evidence on the prognostic role of Prognostic Nutritional Index (PNI) and Controlling Nutritional Status (CONUT) in predicting survival of older adult cancer patients. A comprehensive search was conducted in PubMed and Web of Science Core Collection databases until 22 February 2024. The articles included in this review (n = 38) examined the relationships of PNI and CONUT with survival outcomes in elderly cancer patients. Despite high heterogeneity between the studies, most concluded that low PNI values are associated with poor overall survival (OS), particularly in gastric cancer patients. Most studies did not find an association between PNI and cancer-specific survival, progression-free survival, disease-free survival, recurrence-free survival, and mortality. Results regarding the prognostic role of CONUT in predicting survival were inconclusive. This study suggests that PNI could be used to predict OS in elderly cancer patients, while more studies are needed to assess the prognostic role of CONUT.

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