Preparation and characterisation of solid state forms of paracetamol-O-glucuronide

Preparation of Methyl 1,2,3,4‐tetra‐ O ‐acetyl‐β‐ D ‐glucopyranuronate

“…It has also seen utility for access to and characterization of the important glucuronide-containing metabolite 5 (Scheme 2, C). 5 Importantly, 2 also serves as a vital precursor for the formation of alternative C-1 anomeric derivatives 4 (complicit to wider glycosylation applications and methodologies) including trichloroacetimidates, 5 hemi-acetals, 6 and glycosyl bromides 7 (Scheme 2, B). …”

Discovery of Glycosylated Genipin Derivatives as Novel Antiviral, Insecticidal, and Fungicidal Agents

“…The synthetic procedure for trichloroacetimidate donors 2,3,4,6-tetra- O -acetyl-α- d -glucopyranosyl trichloroacetimidate ( 3a ), 2,3,4,6-tetra- O -acetyl-α- d -galactopyranosyl trichloroacetimidate ( 3b ), 2,3,4,6-tetra- O -acetyl-α- d -mannopyranosyl trichloroacetimidate ( 3c ), 2,3,4-tri- O -acetyl-α- d -xylopyranosyl trichloroacetimidate ( 3d ), 2,3,4-tri- O -acetyl-α- d -glucuronide methyl ester trichloroacetimidate ( 3e ), 2,3,4-tri- O -acetyl-α- l -rhamnopyranosyl trichloroacetimidate ( 3f ), and 2,3,6,2,3′,4′,6′-hepta- O -acetyl-α-maltosyl trichloroacetimidate ( 3g ) was performed according to the published literature. − …”

Crystal Polymorphism of Methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-α-d-glucopyranouronate

“…All solvents were either of HPLC grade or distilled prior to use. Synthesis of the target glycoside donor was as follows [6,9]: …”